ID   U-266/84
AC   CVCL_0016
DR   Wikidata; Q54973558
RX   PubMed=3133230;
WW   https://www.proteinatlas.org/learn/cellines
CC   Characteristics: Produces IgE lambda.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7329; MSH6; Simple; p.Gly141Asp (c.422G>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line).
CC   Omics: Deep antibody staining analysis.
CC   Omics: Deep RNAseq analysis.
CC   Derived from sampling site: Peripheral blood.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0566 ! U266B1
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 20-05-21; Version: 17
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RX   PubMed=3133230; DOI=10.1002/eji.1830180611;
RA   Hellman L., Josephson S., Jernberg H., Nilsson K., Pettersson U.;
RT   "Immunoglobulin synthesis in the human myeloma cell line U-266;
RT   expression of two immunoglobulin heavy chain isotypes (epsilon and
RT   alpha) after long-term cultivation in vitro.";
RL   Eur. J. Immunol. 18:905-910(1988).
//