Cellosaurus U-698-M (CVCL_0017)

Cell line name U-698-M
Synonyms U-698 M; U-698M; U698-M; U698M; U-698; U698
Accession CVCL_0017
Resource Identification Initiative To cite this cell line use: U-698-M (RRID:CVCL_0017)
Comments Part of: MD Anderson Cell Lines Project.
Doubling time: ~48 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep antibody staining analysis.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Lymphoblastic lymphoma (NCIt: C9360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO12
D13S31711,13
D16S53911,12
D18S5115,18
D21S1129,30
D3S135814,15
D5S81811,13
D7S8208,10
D8S117911,13
FGA22,24
Penta D11,12
Penta E11,12
TH016,10
TPOX8
vWA16
Web pages http://www.proteinatlas.org/learn/cellines
http://tcpaportal.org/mclp/
Publications

PubMed=4136723; DOI=10.1002/ijc.2910130609
Nilsson K., Sundstrom C.
Establishment and characteristics of two unique cell lines from patients with lymphosarcoma.
Int. J. Cancer 13:808-823(1974)

PubMed=4369887; DOI=10.1073/pnas.71.8.3283
Klein G., Lindahl T., Jondal M., Leibold W., Menezes J., Nilsson K., Sundstrom C.
Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas.
Proc. Natl. Acad. Sci. U.S.A. 71:3283-3286(1974)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections DSMZ; ACC-4
Cell line databases/resources CLDB; cl4591
Cosmic-CLP; 909777
GDSC; 909777
LINCS_LDP; LCL-1008
Ontologies CLO; CLO_0009462
EFO; EFO_0006768
Biological sample resources BioSample; SAMN03471071
Chemistry resources ChEMBL-Cells; CHEMBL3308280
ChEMBL-Targets; CHEMBL2366098
Gene expression databases GEO; GSM1374973
GEO; GSM1670558
Polymorphism and mutation databases Cosmic; 909777