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Cellosaurus D341 Med (CVCL_0018)

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Cell line name D341 Med
Synonyms D-341 Med; D-341 MED; D-341Med; D-341MED; D341Med; D341MD; D341; Med 341; H341
Accession CVCL_0018
Resource Identification Initiative To cite this cell line use: D341 Med (RRID:CVCL_0018)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: ENCODE project common cell types; tier 3.
Doubling time: 37 hours (ATCC).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Miscellaneous: The values for the STR markers F13A01, F13B, FESFPS and LPL used to be shown on the ATCC website but are no longer displayed (see Internet archive link for archival version).
Disease Medulloblastoma (NCIt: C3222)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3Y5M
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12
D7S8209,13
D13S31711,13
D16S53912,14
F13A016,7
F13B8,10
FESFPS10,13
LPL11
TH016,9.3
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Web pages http://genome.ucsc.edu/ENCODE/protocols/cell/human/MedulloD341_Crawford_protocol.pdf
https://web.archive.org/web/20160611152450/http://www.atcc.org:80/products/all/HTB-187.aspx#specifications
Publications

PubMed=3279793
Friedman H.S., Burger P.C., Bigner S.H., Trojanowski J.Q., Brodeur G.M., He X.-M., Wikstrand C.J., Kurtzberg J., Berens M.E., Halperin E.C., Bigner D.D.
Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc.
Am. J. Pathol. 130:472-484(1988)

PubMed=1822845
Wikstrand C.J., Friedman H.S., Bigner D.D.
Medulloblastoma cell-substrate interaction in vitro.
Invasion Metastasis 11:310-324(1991)

PubMed=8275086; DOI=10.1038/ng1193-230
Galili N., Davis R.J., Fredericks W.J., Mukhopadhyay S., Rauscher F.J. III, Emanuel B.S., Rovera G., Barr F.G.
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma.
Nat. Genet. 5:230-235(1993)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections ATCC; HTB-187
Cell line databases/resources CCLE; D341MED_CENTRAL_NERVOUS_SYSTEM
CCRID; 3111C0001CCC000102
IGRhCellID; D341Med
Ontologies CLO; CLO_0002677
EFO; EFO_0002157
Biological sample resources BioSample; SAMN03472737
ENCODE; ENCBS254AAA
Chemistry resources ChEMBL-Cells; CHEMBL3308450
ChEMBL-Targets; CHEMBL614478
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM482333
GEO; GSM827339
GEO; GSM886970
GEO; GSM888039
GEO; GSM918117
GEO; GSM919358
GEO; GSM1008577
Other Wikidata; Q54817217
Polymorphism and mutation databases Cosmic; 923657
Cosmic; 973263
Cosmic; 974282
Cosmic; 975025
Cosmic; 1097759
Cosmic; 2362652