Cellosaurus SCLC-21H (CVCL_0024)

Cell line name SCLC-21H
Accession CVCL_0024
Resource Identification Initiative To cite this cell line use: SCLC-21H (RRID:CVCL_0024)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: >45 hours (PubMed=2438285); ~2 days (DSMZ).
Omics: Deep antibody staining analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Small cell lung carcinoma (NCIt: C4917)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_X025 (SCLC-16HC); CVCL_8262 (SCLC-24H)
Originate from same individual CVCL_2186 ! SCLC-22H
Sex of cell Male
Category Cancer cell line
STR profile Source(s): CLS; DSMZ; PubMed=11416159; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10
D13S31712
D16S53912
D18S5114,15
D21S1129,31.2
D3S135815
D5S81811,12
D7S82011
D8S117912,13
FGA22 (CLS)
22,23 (PubMed=11416159; PubMed=25877200)
Penta D9
Penta E12,13
TH019.3
TPOX8,9
vWA17
Web pages http://www.proteinatlas.org/learn/cellines
Publications

PubMed=2438285; DOI=10.1007/BF00396382
Bepler G., Jaques G., Koehler A., Gropp C., Havemann K.
Markers and characteristics of human SCLC cell lines. Neuroendocrine markers, classical tumor markers, and chromosomal characteristics of permanent human small cell lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 113:253-259(1987)

PubMed=3029138; DOI=10.1007/BF00389964
Bepler G., Jaques G., Neumann K., Aumuller G., Gropp C., Havemann K.
Establishment, growth properties, and morphological characteristics of permanent human small cell lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 113:31-40(1987)

PubMed=11414198; DOI=10.1007/s004320000207
Lahm H., Andre S., Hoeflich A., Fischer J.R., Sordat B., Kaltner H., Wolf E., Gabius H.J.
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.
J. Cancer Res. Clin. Oncol. 127:375-386(2001)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line collections CLS; 300225/p722_SCLC-21H
DSMZ; ACC-372
Cell line databases/resources CCLE; SCLC21H_LUNG
GDSC; 753611
LINCS_LDP; LCL-1822
Ontologies CLO; CLO_0008972
EFO; EFO_0006749
Biological sample resources BioSample; SAMN03473050
Chemistry resources ChEMBL-Cells; CHEMBL3308465
ChEMBL-Targets; CHEMBL1075574
Gene expression databases GEO; GSM784216
GEO; GSM887562
GEO; GSM888645
Polymorphism and mutation databases Cosmic; 753611