Cellosaurus BeWo (CVCL_0044)

Cell line name BeWo
Synonyms BEWO; Be Wo; Be-Wo
Accession CVCL_0044
Resource Identification Initiative To cite this cell line use: BeWo (RRID:CVCL_0044)
Comments Doubling time: ~30 hours (DSMZ).
Omics: Deep antibody staining analysis.
Omics: Deep RNAseq analysis.
Omics: Transcriptome analysis.
Disease Gestational choriocarcinoma (NCIt: C4646)
Derived from metastatic site: Brain.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_LB82 (BeWo b24); CVCL_LB83 (BeWo b30); CVCL_R702 (Hs 630.T)
Originate from same individual CVCL_0363 ! JEG-3
Sex of cell Male
Category Cancer cell line
STR profile Source(s): AddexBio; ATCC; CLS; DSMZ; ECACC; KCLB; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO11,12
D13S3179,11
D16S53913,14
D18S5114,16
D21S1130
D3S135815
D5S81810,11
D7S82010,12
D8S117912
FGA22,23,24 (CLS)
22,23 (KCLB)
Penta D9,12
Penta E8,12
TH019,9.3
TPOX8
vWA16
Web pages http://www.proteinatlas.org/learn/cellines
http://www2.kumc.edu/soalab/LabLinks/recipes/bewo.htm
http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-163.html
Publications

PubMed=14207855; DOI=10.1093/jnci/33.3.441
Dawe C.J., Banfield W.G., Morgan W.D., Slatick M.S., Curth H.O.
Growth in continuous culture, and in hamsters, of cells from a neoplasm associated with acanthosis nigricans.
J. Natl. Cancer Inst. 33:441-456(1964)

PubMed=4299001
Pattillo R.A., Gey G.O.
The establishment of a cell line of human hormone-synthesizing trophoblastic cells in vitro.
Cancer Res. 28:1231-1236(1968)

PubMed=5753554; DOI=10.1126/science.159.3822.1467
Pattillo R.A., Gey G.O., Delfs E., Mattingly R.F.
Human hormone production in vitro.
Science 159:1467-1469(1968)

PubMed=6174649
Sekiya S., Kawata M., Inaba N., Takamizawa H.
Studies on marker substances in cell lines derived from various human gynecologic tumors.
Nippon Sanka Fujinka Gakkai Zasshi 34:37-42(1982)

PubMed=7153601
Sasaki S., Katayama P.K., Roesler M., Pattillo R.A., Mattingly R.F., Ohkawa K.
Cytogenetic analysis of choriocarcinoma cell lines.
Nippon Sanka Fujinka Gakkai Zasshi 34:2253-2256(1982)

PubMed=4038916; DOI=10.1016/0165-4608(85)90052-4
Sheppard D.M., Fisher R.A., Lawler S.D.
Karyotypic analysis and chromosome polymorphisms in four choriocarcinoma cell lines.
Cancer Genet. Cytogenet. 16:251-258(1985)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2720636; DOI=10.1016/0165-4608(89)90664-X
Surti U., Habibian R.
Chromosomal rearrangement in choriocarcinoma cell lines.
Cancer Genet. Cytogenet. 38:229-240(1989)

PubMed=7937597; DOI=10.1016/0143-4004(94)90008-6
Grummer R., Hohn H.-P., Mareel M.M., Denker H.-W.
Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system.
Placenta 15:411-429(1994)

PubMed=11897413; DOI=10.1016/S0378-5173(01)00929-2
Ampasavate C., Chandorkar G.A., Vande Velde D.G., Stobaugh J.F., Audus K.L.
Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier.
Int. J. Pharm. 233:85-98(2002)

PubMed=16797695; DOI=10.1016/j.placenta.2006.05.001
Burleigh D.W., Kendziorski C.M., Choi Y.J., Grindle K.M., Grendell R.L., Magness R.R., Golos T.G.
Microarray analysis of BeWo and JEG3 trophoblast cell lines: identification of differentially expressed transcripts.
Placenta 28:383-389(2007)

Cross-references
Cell line collections AddexBio; C0030001/4905
ATCC; CCL-98
BCRC; 60073
BCRJ; 0048
CLS; 300123/p643_BEWO
DSMZ; ACC-458
ECACC; 86082803
IZSLER; BS TCL 3
JCRB; JCRB9111
KCLB; 10098
RCB; RCB1644
RCB; RCB3678
TKG; TKG 0567
Cell line databases/resources CLDB; cl415
CLDB; cl416
CCRID; 3111C0001CCC000156
CCRID; 3142C0001000000071
IGRhCellID; BeWo
IMGT/HLA; 10312
LINCS_LDP; LCL-1293
Lonza; 1449
TOKU-E; 661
Ontologies BTO; BTO:0000798
CLO; CLO_0001934
CLO; CLO_0001935
CLO; CLO_0050014
EFO; EFO_0002050
Biological sample resources BioSample; SAMN01821537
BioSample; SAMN01821617
BioSample; SAMN03471293
Chemistry resources ChEMBL-Cells; CHEMBL3308359
ChEMBL-Targets; CHEMBL614525
Gene expression databases GEO; GSM48269
GEO; GSM48270
GEO; GSM48271
GEO; GSM48272
GEO; GSM48273