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Cellosaurus HUES 9 (CVCL_0057)

[Text version]

Cell line name HUES 9
Synonyms HUES-9; HUES9; HuES9; Hues9; HVRDe009-A
Accession CVCL_0057
Resource Identification Initiative To cite this cell line use: HUES 9 (RRID:CVCL_0057)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0022.
Registration: Swiss research registry; BAG-hES-IMP-0039.
Registration: UK Stem Cell Bank (UKSCB); R-05-037, Steering comm. appl. SCSC04-25(9).
Doubling time: 24 hours (PubMed=14999088).
Omics: Deep phosphoproteome analysis.
Omics: Deep proteome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798; PubMed=21637780

Markers:
AmelogeninX
CSF1PO10
D3S135817,18
D5S81812
D7S8208,12
D8S11799,12
D13S31711,12
D16S53912,13
D18S5112,13
D21S1129,30
FGA19,21
Penta D9,13
Penta E10,12
TH018,9
TPOX8,9
vWA17,19

Run an STR similarity search on this cell line
Web pages https://grants.nih.gov/stem_cells/registry/current.htm?id=40
Publications

PubMed=14999088; DOI=10.1056/NEJMsr040330
Cowan C.A., Klimanskaya I., McMahon J., Atienza J., Witmyer J., Zucker J.P., Wang S., Morton C.C., McMahon A.P., Powers D., Melton D.A.
Derivation of embryonic stem-cell lines from human blastocysts.
N. Engl. J. Med. 350:1353-1356(2004)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M., Pedersen R., Pera M.F., Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D., Weaver T.A., Young L.A., Zhang W.
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001
Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032
Bock C., Kiskinis E., Verstappen G., Gu H., Boulting G., Smith Z.D., Ziller M., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=21406692; DOI=10.1126/scisignal.2001570
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
Sci. Signal. 4:Rs3-Rs3(2011)

PubMed=21637780; DOI=10.1371/journal.pgen.1002085
Nishino K., Toyoda M., Yamazaki-Inoue M., Fukawatase Y., Chikazawa E., Sakaguchi H., Akutsu H., Umezawa A.
DNA methylation dynamics in human induced pluripotent stem cells over time.
PLoS Genet. 7:E1002085-E1002085(2011)

PubMed=29861859; DOI=10.18632/oncotarget.25353
Panova A.V., Bogomazova A.N., Lagarkova M.A., Kiselev S.L.
Epigenetic reprogramming by naive conditions establishes an irreversible state of partial X chromosome reactivation in female stem cells.
Oncotarget 9:25136-25147(2018)

Cross-references
Cell line databases/resources hPSCreg; HVRDe009-A
ISCR; 110
SKIP; SKIP001492
SKIP; SKIP001913
Ontologies EFO; EFO_0007094
Biological sample resources eagle-i; harvard.eagle-i.net/i/00000140-2fdc-4c7e-a870-ad6980000000
ENCODE; ENCBS579EEW
Gene expression databases GEO; GSM608014
GEO; GSM608031
GEO; GSM621718
GEO; GSM637762
Other Wikidata; Q54896821
Entry history
Entry creation04-Apr-2012
Last entry updated19-Dec-2019
Version number19