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Cellosaurus SNU-484 (CVCL_0100)

[Text version]
Cell line name SNU-484
Synonyms SNU484
Accession CVCL_0100
Resource Identification Initiative To cite this cell line use: SNU-484 (RRID:CVCL_0100)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 34 hours (PubMed=29435981).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Homozygous (PubMed=9033653).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*24:02,24:02
HLA-BB*44:05,51:01
HLA-CC*05:01,14:02
Class II
HLA-DQDQB1*04:01,04:01

Source: PubMed=26589293
Class I
HLA-AA*24:02,30:01
HLA-BB*44:02,51:01
HLA-CC*05:01,14:02
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C1NA (SNU-484 Ola-R)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): KCLB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO9
D3S135818
D5S81810
D7S82012
D8S117914
D13S31711,12
D16S53913
D18S5113,15
D21S1130
FGA19,23
Penta D12
Penta E22
TH017
TPOX8
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=9033653; DOI=10.1002/(SICI)1097-0215(19970207)70:4<443::AID-IJC12>3.0.CO;2-G
Park J.-G., Yang H.-K., Kim W.-H., Chung J.-K., Kang M.-S., Lee J.-H., Oh J.H., Park H.-S., Yeo K.-S., Kang S.H., Song S.-Y., Kang Y.K., Bang Y.-J., Kim Y.I., Kim J.-P.
Establishment and characterization of human gastric carcinoma cell lines.
Int. J. Cancer 70:443-449(1997)

PubMed=10812166; DOI=10.1016/S0165-4608(99)00217-4
Chun Y.-H., Kil J.-I., Suh Y.-S., Kim S.-H., Kim H., Park S.-H.
Characterization of chromosomal aberrations in human gastric carcinoma cell lines using chromosome painting.
Cancer Genet. Cytogenet. 119:18-25(2000)

PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x
Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H., Okanoue T., Inazawa J.
Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.
Cancer Sci. 96:100-110(2005)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=18804159; DOI=10.1016/j.ygeno.2008.08.002
Jung J.-J., Jeung H.-C., Chung H.C., Lee J.O., Kim T.S., Kim Y.T., Noh S.H., Rha S.Y.
In vitro pharmacogenomic database and chemosensitivity predictive genes in gastric cancer.
Genomics 93:52-61(2009)

PubMed=24807215; DOI=10.1038/ncomms4830
Liu J.-F., McCleland M.L., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H.-B., Wan Y.-N., Chopra V.S., Yaylaoglu M.B., Yuan W.-L., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.-M.
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830.1-3830.8(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=29435981; DOI=10.1002/ijc.31304
Kim H.J., Kang S.K., Kwon W.S., Kim T.S., Jeong I., Jeung H.-C., Kragh M., Horak I.D., Chung H.C., Rha S.Y.
Forty-nine gastric cancer cell lines with integrative genomic profiling for development of c-MET inhibitor.
Int. J. Cancer 143:151-159(2018)

PubMed=32028591; DOI=10.3390/cancers12020334
Kim J.W., Min A., Im S.-A., Jang H., Kim Y.J., Kim H.-J., Lee K.-H., Kim T.-Y., Lee K.W., Oh D.-Y., Kim J.-H., Bang Y.-J.
TDP1 and TOP1 modulation in olaparib-resistant cancer determines the efficacy of subsequent chemotherapy.
Cancers (Basel) 12:334.1-334.17(2020)

Cross-references
Cell line collections (Providers) KCLB; 00484
Cell line databases/resources cancercelllines; CVCL_0100
CGH-DB; 125-1
CGH-DB; 9013-4
Anatomy/cell type resources BTO; BTO:0003479
Biological sample resources BioSample; SAMN03473176
Chemistry resources PharmacoDB; SNU484_1467_2019
Encyclopedic resources Wikidata; Q54955211
Experimental variables resources EFO; EFO_0006755
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM1374892
Polymorphism and mutation databases Cosmic; 685590
Cosmic; 848140
Cosmic; 921598
Cosmic; 1067206
Cosmic; 1090454
Cosmic; 1294958
Cosmic; 1528875
Cosmic; 2484965
Cosmic; 2646591
Cosmic; 2807646
IARC_TP53; 7419
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number31