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Cellosaurus JY (CVCL_0108)

[Text version]

Cell line name JY
Synonyms JY-S
Accession CVCL_0108
Resource Identification Initiative To cite this cell line use: JY (RRID:CVCL_0108)
Comments Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Population: Caucasian; Amish.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep RNAseq analysis.
Omics: HLA class I peptidome analysis by proteomics.
Omics: MHC region genome.
Derived from sampling site: Peripheral blood.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*02:01,02:01
HLA-BB*07:02,07:02
HLA-CC*07:02,07:02
Class II
HLA-DQDQA1*03:02,01:03
DQB1*06:11,03:02
HLA-DRDRB1*04:04,13:01

Source: IPD-IMGT/HLA; 10882
Class I
HLA-AA*02:01:01:01
HLA-BB*07:02:01:01
HLA-CC*07:02:01:01,07:02:01:03
Class II
HLA-DPDPA1*01:03
DPB1*02:01:02:01,04:01
HLA-DQDQA1*01:03,03:01:01
DQB1*03:02;06:03
HLA-DRDRA*01:01:01:01,01:02:01
DRB1*04:04,13:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Web pages https://en.wikipedia.org/wiki/JY_cell_line
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/j/cell-lines-detail-50.html
Publications

PubMed=6294325; DOI=10.1128/JVI.44.3.1088-1091.1982
Skare J., Edson C., Farley J., Strominger J.L.
The B95-8 isolate of Epstein-Barr virus arose from an isolate with a standard genome.
J. Virol. 44:1088-1091(1982)

PubMed=6417007; DOI=10.1007/BF00364387
Bono M.R., Strominger J.L.
NH2-terminal sequence of the alpha and beta chains of human DC-1 antigen isolated from the JY cell line. Homology with murine I-A molecules.
Immunogenetics 18:453-459(1983)

PubMed=23619976; DOI=10.1007/s00262-013-1412-z
Neumann F., Kaddu-Mulindwa D., Widmann T., Preuss K.-D., Held G., Zwick C., Roemer K., Pfreundschuh M., Kubuschok B.
EBV-transformed lymphoblastoid cell lines as vaccines against cancer testis antigen-positive tumors.
Cancer Immunol. Immunother. 62:1211-1222(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25576301; DOI=10.1074/mcp.M114.042812
Bassani-Sternberg M., Pletscher-Frankild S., Jensen L.J., Mann M.
Mass spectrometry of human leukocyte antigen class I peptidomes reveals strong effects of protein abundance and turnover on antigen presentation.
Mol. Cell. Proteomics 14:658-673(2015)

PubMed=28360230; DOI=10.1101/gr.213538.116
Norman P.J., Norberg S.J., Guethlein L.A., Nemat-Gorgani N., Royce T., Wroblewski E.E., Dunn T., Mann T., Alicata C., Hollenbach J.A., Chang W., Shults Won M., Gunderson K.L., Abi-Rached L., Ronaghi M., Parham P.
Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.
Genome Res. 27:813-823(2017)

PubMed=30844424; DOI=10.1016/j.humimm.2019.03.001
Creary L.E., Guerra S.G., Chong W., Brown C.J., Turner T.R., Robinson J., Bultitude W.P., Mayor N.P., Marsh S.G.E., Saito K., Lam K., Duke J.L., Mosbruger T.L., Ferriola D., Monos D., Willis A., Askar M., Fischer G., Saw C.L., Ragoussis J., Petrek M., Serra-Pages C., Juan M., Stavropoulos-Giokas C., Dinou A., Ameen R., Al Shemmari S., Spierings E., Gendzekhadze K., Morris G.P., Zhang Q.-H., Kashi Z., Hsu S., Gangavarapu S., Mallempati K.C., Yamamoto F., Osoegawa K., Vayntrub T., Chang C.-J., Hansen J.A., Fernandez-Vina M.A.
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop.
Hum. Immunol. 80:449-460(2019)

Cross-references
Cell line collections ECACC; 94022533
Cell line databases/resources dbMHC; 48917
IHW; IHW09287
IPD-IMGT/HLA; 10882
Ontologies BTO; BTO:0003044
CLO; CLO_0037202
Chemistry resources ChEMBL-Cells; CHEMBL3308061
ChEMBL-Targets; CHEMBL613833
Other Wikidata; Q6109290
Proteomic databases PRIDE; PXD000394
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number21