Cellosaurus

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Cellosaurus JY (CVCL_0108)

[Text version]

Cell line name

Synonyms

JY-S

Accession

CVCL_0108

Resource Identification Initiative

To cite this cell line use: JY (RRID:CVCL_0108)

Comments

Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep RNAseq analysis.
Omics: HLA class I peptidome analysis by proteomics.
Omics: MHC region genome.

HLA typing

Source: PubMed=25960936

Class I
HLA-A	A*02:01,02:01
HLA-B	B*07:02,07:02
HLA-C	C*07:02,07:02
Class II
HLA-DQ	DQA1*03:02,01:03
	DQB1*06:11,03:02
HLA-DR	DRB1*04:04,13:01

Source: IPD-IMGT/HLA; 10882

Class I
HLA-A	A*02:01:01:01
HLA-B	B*07:02:01:01
HLA-C	C*07:02:01:01,07:02:01:03
Class II
HLA-DP	DPA1*01:03
	DPB1*02:01:02:01,04:01
HLA-DQ	DQA1*01:03,03:01:01
	DQB1*03:02;06:03
HLA-DR	DRA*01:01:01:01,01:02:01
	DRB1*04:04,13:01

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Category

Transformed cell line

Web pages

https://en.wikipedia.org/wiki/JY_cell_line
http://bioinformatics.hsanmartino.it/ecbr/cl287.html
http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/j/cell-lines-detail-50.html

Publications

PubMed=6417007; DOI=10.1007/BF00364387
Bono M.R., Strominger J.L.
NH2-terminal sequence of the alpha and beta chains of human DC-1 antigen isolated from the JY cell line. Homology with murine I-A molecules.
Immunogenetics 18:453-459(1983)

PubMed=23619976; DOI=10.1007/s00262-013-1412-z
Neumann F., Kaddu-Mulindwa D., Widmann T., Preuss K.-D., Held G., Zwick C., Roemer K., Pfreundschuh M., Kubuschok B.
EBV-transformed lymphoblastoid cell lines as vaccines against cancer testis antigen-positive tumors.
Cancer Immunol. Immunother. 62:1211-1222(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

PubMed=25576301; DOI=10.1074/mcp.M114.042812
Bassani-Sternberg M., Pletscher-Frankild S., Jensen L.J., Mann M.
Mass spectrometry of human leukocyte antigen class I peptidomes reveals strong effects of protein abundance and turnover on antigen presentation.
Mol. Cell. Proteomics 14:658-673(2015)

PubMed=28360230; DOI=10.1101/gr.213538.116
Norman P.J., Norberg S.J., Guethlein L.A., Nemat-Gorgani N., Royce T., Wroblewski E.E., Dunn T., Mann T., Alicata C., Hollenbach J.A., Chang W., Shults Won M., Gunderson K.L., Abi-Rached L., Ronaghi M., Parham P.
Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.
Genome Res. 27:813-823(2017)

Cross-references

Cell line collections

ECACC; 94022533

Cell line databases/resources

dbMHC; 48917
IHW; IHW09287
IPD-IMGT/HLA; 10882

Ontologies

BTO; BTO:0003044
CLO; CLO_0037202

Chemistry resources

ChEMBL-Cells; CHEMBL3308061
ChEMBL-Targets; CHEMBL613833

Other

Wikidata; Q6109290

Proteomic databases