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Cellosaurus 435.eB (CVCL_0124)

Cell line name 435.eB
Accession CVCL_0124
Resource Identification Initiative To cite this cell line use: 435.eB (RRID:CVCL_0124)
Comments Problematic cell line: Contaminated. Parent cell line (MDA-MB-435) has been shown to be a M14 derivative.
Transfected with: HGNC; 3430; ERBB2.
Sequence variations Heterozygous for BRAF p.Val600Glu (c.1799T>A) (from parent cell line).
Heterozygous for CDKN2A c.150+2T>C (IVS1+2T>C) and c.455insCdel26 (from parent cell line).
Heterozygous for TP53 p.Gly266Glu (c.797G>A) (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Derived from metastatic site: Subcutaneous; right buttock.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0417 (MDA-MB-435)
Sex of cell Male
Age at sampling 33Y
Category Cancer cell line
Ontologies MCCL; MCC:0000016
Other Wikidata; Q54603035