ID   B16-F1
AC   CVCL_0158
SY   B16/F1; B16 F1; B16F1
DR   BTO; BTO:0003853
DR   CLO; CLO_0001793
DR   CLO; CLO_0050764
DR   MCCL; MCC:0000050
DR   CLDB; cl337
DR   CLDB; cl338
DR   ATCC; CRL-6323
DR   BCRC; 60030
DR   BCRJ; 0045
DR   BioSample; SAMN11397654
DR   CCRID; 1101MOU-PUMC000365
DR   CCRID; 4201MOU-CCTCC00039
DR   CCTCC; GDC0039
DR   ChEMBL-Cells; CHEMBL4295385
DR   ChEMBL-Targets; CHEMBL4296402
DR   CLS; 400122
DR   ECACC; 92101203
DR   KCLB; 80007
DR   Lonza; 1278
DR   NCI-DTP; B16F1
DR   PRIDE; PXD018083
DR   PubChem_Cell_line; CVCL_0158
DR   RCB; RCB2649
DR   TKG; TKG 0347
DR   TOKU-E; 581
DR   Wikidata; Q54752433
RX   PubMed=210294;
RX   PubMed=1109790;
RX   PubMed=6498800;
RX   PubMed=6539703;
RX   PubMed=11833741;
RX   PubMed=22797548;
RX   PubMed=25277546;
RX   PubMed=31220119;
RX   PubMed=33596583;
CC   Characteristics: Obtained from the pulmonary melanoma module of the 1st serial passage of the B16-F0 parent cell line in C57BL/6 mice.
CC   Characteristics: Has a low metastatic potential.
CC   Doubling time: 22 hours (PubMed=1109790).
CC   Karyotypic information: Near tetraploid karyotype (PubMed=33596583).
CC   Omics: Array-based CGH.
CC   Omics: SNP array analysis.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Breed/subspecies: C57BL/6.
ST   Source(s): PubMed=31220119
ST   Mouse STR 1-1: 17,18
ST   Mouse STR 1-2: 19,20
ST   Mouse STR 11-2: 16,17
ST   Mouse STR 12-1: 17,18
ST   Mouse STR 13-1: 17,18
ST   Mouse STR 15-3: 22.3,23.3
ST   Mouse STR 17-2: 15,16,17
ST   Mouse STR 18-3: 15,16
ST   Mouse STR 19-2: 13
ST   Mouse STR 2-1: 16
ST   Mouse STR 3-2: 14,15
ST   Mouse STR 4-2: 20.3,21.3
ST   Mouse STR 5-5: 16,20
ST   Mouse STR 6-4: 18,19
ST   Mouse STR 6-7: 15
ST   Mouse STR 7-1: 26.2
ST   Mouse STR 8-1: 16,17
ST   Mouse STR X-1: 28
DI   NCIt; C21790; Mouse melanoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0604 ! B16-F0
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 27
//
RX   PubMed=210294; DOI=10.1093/jnci/61.2.523;
RA   Niles R.M., Makarski J.S.;
RT   "Control of melanogenesis in mouse melanoma cells of varying
RT   metastatic potential.";
RL   J. Natl. Cancer Inst. 61:523-526(1978).
//
RX   PubMed=1109790;
RA   Fidler I.J.;
RT   "Biological behavior of malignant melanoma cells correlated to their
RT   survival in vivo.";
RL   Cancer Res. 35:218-224(1975).
//
RX   PubMed=6498800; DOI=10.1016/0304-3835(84)90080-6;
RA   Wosko T.J., Ferrara D.T., Sartori L.S.;
RT   "Histological comparison of the B16 melanoma and its F1 variant.";
RL   Cancer Lett. 24:57-63(1984).
//
RX   PubMed=6539703; DOI=10.1016/0277-5379(84)90015-4;
RA   Weinreb A., Travo P.;
RT   "Discrimination between human melanoma cell lines by fluorescence
RT   anisotropy.";
RL   Eur. J. Cancer Clin. Oncol. 20:673-677(1984).
//
RX   PubMed=11833741; DOI=10.1016/S0024-3205(01)01454-0;
RA   Nakamura K., Yoshikawa N., Yamaguchi Y., Kagota S., Shinozuka K.,
RA   Kunitomo M.;
RT   "Characterization of mouse melanoma cell lines by their mortal
RT   malignancy using an experimental metastatic model.";
RL   Life Sci. 70:791-798(2002).
//
RX   PubMed=22797548; DOI=10.3892/ijo.2012.1548;
RA   Liersch R., Shin J.W., Bayer M., Schwoppe C., Schliemann C.,
RA   Berdel W.E., Mesters R., Detmar M.;
RT   "Analysis of a novel highly metastatic melanoma cell line identifies
RT   osteopontin as a new lymphangiogenic factor.";
RL   Int. J. Oncol. 41:1455-1463(2012).
//
RX   PubMed=25277546; DOI=10.1186/1471-2164-15-847;
RA   Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W.,
RA   Morse H.C. III, Pardo-Manuel de Villena F.;
RT   "SNP array profiling of mouse cell lines identifies their strains of
RT   origin and reveals cross-contamination and widespread aneuploidy.";
RL   BMC Genomics 15:847.1-847.11(2014).
//
RX   PubMed=31220119; DOI=10.1371/journal.pone.0218412;
RA   Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S.,
RA   Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H.,
RA   Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B.,
RA   Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.;
RT   "Interlaboratory study to validate a STR profiling method for
RT   intraspecies identification of mouse cell lines.";
RL   PLoS ONE 14:E0218412-E0218412(2019).
//
RX   PubMed=33596583; DOI=10.1159/000513174;
RA   Piaszinski K., Rincic M., Liehr T., Azawi S.;
RT   "Molecular cytogenetic characterization of the murine melanoma cell
RT   lines S91 clone M3 and B16-F1 with variant B16-4A5.";
RL   Cytogenet. Genome Res. 161:82-92(2021).
//