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Cellosaurus Beta-TC-3 (CVCL_0172)

Cell line name Beta-TC-3
Synonyms beta-TC-3; beta-TC3; beta TC3; BETA-TC-3; BETATC3; BetaTC3; betaTC3; bTC3
Accession CVCL_0172
Resource Identification Initiative To cite this cell line use: Beta-TC-3 (RRID:CVCL_0172)
Comments Doubling time: ~34 hours (DSMZ=ACC-324).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Mouse insulinoma (NCIt: C34053)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (C57BL/6J x DBA/2J)F2 transgenic RIPTag2.
Category Transformed cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-210.html
Publications

PubMed=2848253; DOI=10.1073/pnas.85.23.9037
Efrat S., Linde S., Kofod H., Spector D.L., Delannoy M., Grant S., Hanahan D., Baekkeskov S.
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.
Proc. Natl. Acad. Sci. U.S.A. 85:9037-9041(1988)

PubMed=1710218; DOI=10.1016/S0021-9258(18)99139-8
Efrat S., Surana M., Fleischer N.
Glucose induces insulin gene transcription in a murine pancreatic beta-cell line.
J. Biol. Chem. 266:11141-11143(1991)

PubMed=22538498; DOI=10.1159/000338793
Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

Cross-references
Cell line collections (Providers) DSMZ; ACC-324
IBRC; C10109
Cell line databases/resources CLO; CLO_0001932
MCCL; MCC:0000063
DSMZCellDive; ACC-324
TOKU-E; 4054
Anatomy/cell type resources BTO; BTO:0002993
Chemistry resources ChEMBL-Cells; CHEMBL3308357
ChEMBL-Targets; CHEMBL614063
PubChem_Cell_line; CVCL_0172
Encyclopedic resources Wikidata; Q54796097
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number20