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Cellosaurus Beta-TC-tet (CVCL_0185)

[Text version]
Cell line name Beta-TC-tet
Synonyms BetaTCtet; betaTC-tet
Accession CVCL_0185
Resource Identification Initiative To cite this cell line use: Beta-TC-tet (RRID:CVCL_0185)
Comments Characteristics: Expression of the SV40 T-antigen is under the control of the tet operator sequence. Shows growth arrest and further differentiation upon addition of 5 ng/ml tetracycline (PubMed=7724601).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3HeB/FeJ.
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Conditionally immortalized cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=betaTC-tet
Publications

PubMed=7724601; DOI=10.1073/pnas.92.8.3576
Efrat S., Fusco-DeMane D., Lemberg H., Al Emran O., Wang X.-R.
Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene.
Proc. Natl. Acad. Sci. U.S.A. 92:3576-3580(1995)

PubMed=11900281; DOI=10.1080/15604280212526
Milo-Landesman D., Efrat S.
Growth factor-dependent proliferation of the pancreatic beta-cell line betaTC-tet: an assay for beta-cell mitogenic factors.
Int. J. Exp. Diabetes Res. 3:69-74(2002)

Cross-references
Cell line collections (Providers) ATCC; CRL-3237
Cell line databases/resources MCCL; MCC:0000076
Encyclopedic resources Wikidata; Q54796105
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13