ID   Caov-4
AC   CVCL_0202
SY   CaOv-4; CaOV-4; CAOV-4; CAOV4; Caov4
DR   CLO; CLO_0002196
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; HTB-76
DR   BioGRID_ORCS_Cell_line; 843
DR   BioSample; SAMN03472755
DR   BioSample; SAMN03472784
DR   BioSample; SAMN10987815
DR   cancercelllines; CVCL_0202
DR   CCRID; 1101HUM-PUMC000367
DR   Cell_Model_Passport; SIDM00918
DR   ChEMBL-Cells; CHEMBL3308232
DR   ChEMBL-Targets; CHEMBL2366249
DR   Cosmic; 688093
DR   Cosmic; 809112
DR   Cosmic; 844350
DR   Cosmic; 849610
DR   Cosmic; 948287
DR   Cosmic; 949090
DR   Cosmic; 949226
DR   Cosmic; 1305321
DR   Cosmic-CLP; 949090
DR   DepMap; ACH-000103
DR   EGA; EGAS00001000978
DR   GDSC; 949090
DR   GEO; GSM784562
DR   GEO; GSM886919
DR   GEO; GSM887985
DR   GEO; GSM1001487
DR   GEO; GSM1291131
DR   GEO; GSM1669662
DR   IARC_TP53; 1414
DR   IARC_TP53; 28484
DR   IARC_TP53; 30198
DR   IGRhCellID; Caov4
DR   IZSLER; BS TCL 183
DR   KCLB; 30076
DR   LiGeA; CCLE_173
DR   LINCS_LDP; LCL-1520
DR   NCBI_Iran; C595
DR   PharmacoDB; Caov4_183_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0202
DR   PubChem_Cell_line; CVCL_0202
DR   Wikidata; Q54808586
RX   PubMed=3518877;
RX   PubMed=6935474;
RX   PubMed=9698466;
RX   PubMed=20164919;
RX   PubMed=20204287;
RX   PubMed=20215515;
RX   PubMed=22460905;
RX   PubMed=23839242;
RX   PubMed=25230021;
RX   PubMed=25877200;
RX   PubMed=25984343;
RX   PubMed=27235858;
RX   PubMed=27397505;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=31395879;
RX   PubMed=35839778;
WW   https://www.mskcc.org/research-advantage/support/technology/tangible-material/caov-4-human-ovarian-cell-line
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: OCCP ovarian cancer cell line panel.
CC   Part of: TCGA-110-CL cell line panel.
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2010-070.
CC   Population: Caucasian.
CC   Doubling time: >120 hours (PubMed=25984343).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val147Asp (c.440T>A); ClinVar=VCV001351017; Zygosity=Homozygous (PubMed=25230021; ATCC).
CC   Omics: Array-based CGH.
CC   Omics: CRISPR phenotypic screen.
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: shRNA library screening.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=0.23%; Native American=0%; East Asian, North=4.8%; East Asian, South=0%; South Asian=0%; European, North=67.03%; European, South=27.94% (PubMed=30894373).
CC   Derived from site: Metastatic; Fallopian tube, subserosa; UBERON=UBERON_8480037.
ST   Source(s): ATCC; CCRID; Cosmic-CLP; KCLB; PubMed=25230021; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10 (CCRID; Cosmic-CLP; KCLB; PubMed=25230021; PubMed=25877200)
ST   CSF1PO: 10,11 (ATCC)
ST   D13S317: 12,14
ST   D16S539: 9,11
ST   D18S51: 21
ST   D19S433: 11,12
ST   D21S11: 28,33.2
ST   D2S1338: 17,20
ST   D3S1358: 16
ST   D5S818: 11 (CCRID; Cosmic-CLP; KCLB; PubMed=25230021; PubMed=25877200)
ST   D5S818: 11,13 (ATCC)
ST   D7S820: 8,10
ST   D8S1179: 12
ST   FGA: 22
ST   Penta D: 9,10
ST   Penta E: 12,13
ST   TH01: 6,9.3
ST   TPOX: 8,9
ST   vWA: 16,17
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   45Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 40
//
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RT   vitro morphological subtypes.";
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RT   control.";
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RA   Noonan A.M., Annunziata C.M.;
RT   "Characterization of ovarian cancer cell lines as in vivo models for
RT   preclinical studies.";
RL   Gynecol. Oncol. 142:332-340(2016).
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RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
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//