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Cellosaurus CHL (CVCL_0212)

[Text version]
Cell line name CHL
Synonyms Chinese Hamster Lung
Accession CVCL_0212
Resource Identification Initiative To cite this cell line use: CHL (RRID:CVCL_0212)
Comments Characteristics: Used in chemical substance-induced chromosomal aberration detection.
Doubling time: ~30 hours (PubMed=5452405); ~14 hours (PubMed=1370240).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Children:
CVCL_UU65 (CHL A-15)CVCL_8483 (CHL AIG)CVCL_UU90 (CHL CR-119)
CVCL_UU70 (CHL CR-50)CVCL_UU71 (CHL CR-52)CVCL_UU72 (CHL CR-68)
CVCL_J390 (CHL-3A4)CVCL_0U07 (CHL-CYP2C18)CVCL_4585 (CHL/IU)
CVCL_8557 (YG10003)CVCL_8558 (YG10007)CVCL_8559 (YG10008)
Sex of cell Female
Age at sampling 1D
Category Spontaneously immortalized cell line
Publications

PubMed=5452405; DOI=10.20772/cancersci1959.61.2_161
Koyama H., Utakoji T., Ono T.
A new cell line derived from newborn Chinese hamster lung tissue.
Gann 61:161-167(1970)

PubMed=1170023; DOI=10.1016/0092-8674(75)90021-5
Miyashita K., Kakunaga T.
Isolation of heat- and cold-sensitive mutants of Chinese hamster lung cells affected in their ability to express the transformed state.
Cell 5:131-138(1975)

PubMed=688393; DOI=10.1016/0092-8674(78)90354-9
Gupta R.S., Chan D.Y.-H., Siminovitch L.
Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis.
Cell 14:1007-1013(1978)

PubMed=3558490; DOI=10.1002/jcp.1041300303
Gupta R.S., Dudani A.K.
Species-specific differences in the toxicity of rhodamine 123 towards cultured mammalian cells.
J. Cell. Physiol. 130:321-327(1987)

PubMed=1370240; DOI=10.1016/0027-5107(92)90036-2
Sawada M., Kitamura R., Kamataki T.
Stable expression of monkey cytochrome P-450IA1 cDNA in Chinese hamster CHL cells and its application for detection of mutagenicity of aflatoxin B1.
Mutat. Res. 265:23-29(1992)

PubMed=7512690; DOI=10.1016/0165-7992(94)90033-7
Ono T., Norimatsu M., Yoshimura H.
Induction of chromosome aberrations by pyrimethamine in cultured Chinese hamster (CHL) cells.
Mutat. Res. 323:197-201(1994)

Cross-references
Cell line collections (Providers) CLS; 305013
ECACC; 87111906
KCB; KCB 93014YJ
KCB; KCB 200811YJ
RCB; RCB0097
Cell line databases/resources CLO; CLO_0002418
CLO; CLO_0051575
MCCL; MCC:0000101
CLDB; cl720
CCRID; 3101HAMGNHa2
CCRID; 5301HAM-KCB08011YJ
Encyclopedic resources Wikidata; Q54812127
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20