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Cellosaurus CTLL-2 (CVCL_0227)

[Text version]

Cell line name CTLL-2
Synonyms CTLL 2; CTLL2; CTLL(2)
Accession CVCL_0227
Resource Identification Initiative To cite this cell line use: CTLL-2 (RRID:CVCL_0227)
Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Characteristics: IL2 dependent.
Doubling time: 24 hours (PubMed=145543).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_KS71 (CellSensor irf1-bla CTLL-2)CVCL_6829 (CT.EV)CVCL_D100 (CTL44)
CVCL_YU23 (CTLL-2 NF-kappaB)CVCL_9786 (CTLL-20)
Category Transformed cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-117
Mouse STR 1-219,20
Mouse STR 2-115,16
Mouse STR 3-214
Mouse STR 4-220.3
Mouse STR 5-517,18
Mouse STR 6-418,19
Mouse STR 6-717,20
Mouse STR 7-126.2
Mouse STR 8-116
Mouse STR 11-216
Mouse STR 12-117
Mouse STR 13-116
Mouse STR 15-322.3,23.3
Mouse STR 17-214,15
Mouse STR 18-316
Mouse STR 19-213,14
Mouse STR X-128,29

Run an STR similarity search on this cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=CTLL-2
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-67.html
Publications

PubMed=145543; DOI=10.1038/268154a0
Gillis S., Smith K.A.
Long term culture of tumour-specific cytotoxic T cells.
Nature 268:154-156(1977)

PubMed=9619491; DOI=10.1046/j.1440-1711.1998.00733.x
Weston L., Geczy A., Farrell C.
A convenient and reliable IL-2 bioassay using frozen CTLL-2 to improve the detection of helper T lymphocyte precursors.
Immunol. Cell Biol. 76:190-192(1998)

PubMed=9744750; DOI=10.1016/S0022-1759(98)00065-9
Winandy M., Lewalle P., Deneys V., Ferrant A., De Bruyere M.
Improved IL-2 detection for determination of helper T lymphocyte precursor frequency in limiting dilution assay.
J. Immunol. Methods 215:81-94(1998)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line collections ATCC; TIB-214
BCRC; 60376
BCRJ; 0281 - Discontinued
CLS; 400482/p779_CTLL-2
DSMZ; ACC-27 - Discontinued
ECACC; 93042610
ICLC; AL00003
NCBI_Iran; C538
RCB; RCB0637
Cell line databases/resources CLDB; cl925
CLDB; cl4995
CCRID; 3111C0002000000051
CCRID; 3131C0001000300004
Lonza; 1012
Ontologies BTO; BTO:0001482
CLO; CLO_0002636
CLO; CLO_0050181
EFO; EFO_0002821
MCCL; MCC:0000115
Biological sample resources BioSample; SAMN11397659
Other Wikidata; Q54814742
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number23