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Cellosaurus Chang Liver (CVCL_0238)

Cell line name Chang Liver
Synonyms Chang liver; Chang Cells
Accession CVCL_0238
Resource Identification Initiative To cite this cell line use: Chang Liver (RRID:CVCL_0238)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=5641128; PubMed=1246601; PubMed=20143388). Originally thought to originate from normal liver hepatic cells.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00002.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Genome sequenced (low read coverage).
Omics: Ubiquitination analysis by proteomics.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): ATCC; CLS; ECACC; JCRB; PubMed=11416159

Markers:
AmelogeninX
CSF1PO10 (ATCC; CLS; ECACC)
9,10 (JCRB)
D13S31712,13.3 (ATCC; CLS; JCRB)
12,14 (ECACC)
D16S5399,10
D18S5116
D21S1127,28
D3S135815,18
D5S81812 (ATCC; CLS; ECACC)
11,12 (JCRB)
D7S8208,12
D8S117912,13
FGA21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18 (ATCC; CLS; ECACC; PubMed=11416159)
16,17,18 (JCRB)
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=13472685
Syverton J.T., McLaren L.C.
Human cells in continuous culture. I. Derivation of cell strains from esophagus, palate, liver, and lung.
Cancer Res. 17:923-926(1957)

PubMed=14185313; DOI=10.1126/science.146.3641.241
Cell Culture Collection Committee
Animal cell strains. The Cell Culture Collection Committee has assembled and certified 23 strains of animal cells.
Science 146:241-243(1964)

PubMed=5641128; DOI=10.1038/217750a0
Gartler S.M.
Apparent Hela cell contamination of human heteroploid cell lines.
Nature 217:750-751(1968)

DOI=10.1007/978-1-4757-1647-4_13
Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

CLPUB00262
Gold M.
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986)

PubMed=18655026; DOI=10.1002/pmic.200700887
Tan F.-W., Lu L.-F., Cai Y., Wang J.-L., Xie Y.-F., Wang L., Gong Y.-H., Xu B.E., Wu J., Luo Y., Qiang B.-Q., Yuan J.-G., Sun X.-Q., Peng X.-Z.
Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells.
Proteomics 8:2885-2896(2008)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=23925245; DOI=10.1038/nature12064
Adey A., Burton J.N., Kitzman J.O., Hiatt J.B., Lewis A.P., Martin B.K., Qiu R., Lee C., Shendure J.
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line.
Nature 500:207-211(2013)

Cross-references
Cell line collections ATCC; CCL-13
CLS; 300139/p774_Chang-Liver_(HeLa)
ECACC; 88021102
IZSLER; BS CL 14
JCRB; IFO50016
JCRB; JCRB9066
RCB; RCB0491 - Discontinued
Cell line databases/resources CLDB; cl715
CLDB; cl716
CLDB; cl717
CLDB; cl718
CCRID; 3131C0001000200009
TOKU-E; 937
Ontologies BTO; BTO:0002049
CLO; CLO_0002414
CLO; CLO_0002415
MCCL; MCC:0000128
Biological sample resources BioSample; SAMN03151672
BioSample; SAMN03472417
BioSample; SAMN03472705
Other Wikidata; Q54811726