ID   GI-101A
AC   CVCL_0278
AS   CVCL_5214
SY   GI101A; GI 101A; GI-101; GI 101; GI101
DR   MCCL; MCC:0000169
DR   cancercelllines; CVCL_0278
DR   Cosmic; 687469
DR   GEO; GSM217569
DR   GEO; GSM219931
DR   Progenetix; CVCL_0278
DR   Wikidata; Q54835803
RX   Patent=US6037520;
RX   PubMed=10328849;
RX   PubMed=12800145;
RX   PubMed=14598885;
WW   https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/GI%20101.html
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12420.
CC   Characteristics: Established from a athymic mice xenograft.
CC   Doubling time: 36 hours (Note=In a medium with 10% serum) (PubMed=14598885).
CC   Omics: miRNA expression profiling.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
DI   NCIt; C4872; Breast carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   57Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 25
//
RX   Patent=US6037520;
RA   Raney S., Emma D., Hurst J.M.;
RT   "Human breast carcinoma cell line capable of production of a
RT   spontaneously metastasizing tumor in animals for use in anticancer
RT   drug testing.";
RL   Patent number US6037520, 14-Mar-2000.
//
RX   PubMed=10328849; DOI=10.1006/cbir.1998.0269;
RA   Morrissey J.J., Raney S.;
RT   "A metastatic breast tumor cell line, GI-101A, is estrogen receptor
RT   positive and responsive to estrogen but resistant to tamoxifen.";
RL   Cell Biol. Int. 22:413-419(1998).
//
RX   PubMed=12800145; DOI=10.1002/gcc.10218;
RA   Adelaide J., Huang H.-E., Murati A., Alsop A.E., Orsetti B.,
RA   Mozziconacci M.-J., Popovici C., Ginestier C., Letessier A.,
RA   Basset C., Courtay-Cahen C., Jacquemier J., Theillet C., Birnbaum D.,
RA   Edwards P.A.W., Chaffanet M.;
RT   "A recurrent chromosome translocation breakpoint in breast and
RT   pancreatic cancer cell lines targets the neuregulin/NRG1 gene.";
RL   Genes Chromosomes Cancer 37:333-345(2003).
//
RX   PubMed=14598885; DOI=10.1023/A:1025837631179;
RA   Lev D.C., Kiriakova G., Price J.E.;
RT   "Selection of more aggressive variants of the GI101A human breast
RT   cancer cell line: a model for analyzing the metastatic phenotype of
RT   breast cancer.";
RL   Clin. Exp. Metastasis 20:515-523(2003).
//