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Cellosaurus H9c2(2-1) (CVCL_0286)

[Text version]
Cell line name H9c2(2-1)
Synonyms H9c2 (2-1); H9c2; H9C2
Accession CVCL_0286
Resource Identification Initiative To cite this cell line use: H9c2(2-1) (RRID:CVCL_0286)
Comments Derived from site: In situ; Embryonic heart, cardiac muscle; UBERON=UBERON_0003084+UBERON_0001133.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: BDIX.
Hierarchy Children:
CVCL_B0FS (H9c2 Trpm4 KO)CVCL_C8V4 (H9C2(2-1)-Luc)CVCL_XE64 (H9C2(2-1)-Luc2-tdT)
CVCL_XE65 (H9C2(2-1)-mCherry)CVCL_XE66 (H9C2(2-1)-tdT)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-409.html
Publications

PubMed=943302; DOI=10.1016/0014-4827(76)90447-X
Kimes B.W., Brandt B.L.
Properties of a clonal muscle cell line from rat heart.
Exp. Cell Res. 98:367-381(1976)

PubMed=1683272; DOI=10.1161/01.RES.69.6.1476
Hescheler J., Meyer R., Plant S., Krautwurst D., Rosenthal W., Schultz G.
Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart.
Circ. Res. 69:1476-1486(1991)

PubMed=17662623; DOI=10.1016/j.vascn.2007.06.001
Zordoky B.N.M., El-Kadi A.O.S.
H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart.
J. Pharmacol. Toxicol. Methods 56:317-322(2007)

PubMed=21082279; DOI=10.1007/s11626-010-9368-1
Watkins S.J., Borthwick G.M., Arthur H.M.
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro.
In Vitro Cell. Dev. Biol. Anim. 47:125-131(2011)

Cross-references
Cell line collections (Providers) AddexBio; C0031002/5017
ATCC; CRL-1446
BCRC; 60096
BCRJ; 0098
CCTCC; GDC0606
CLS; 305203
ECACC; 88092904
IZSLER; BS CL 151
KCLB; 21446
NCBI_Iran; C585
Ubigene; YC-A009
Cell line databases/resources CLO; CLO_0003614
MCCL; MCC:0000176
CLDB; cl1558
CLDB; cl5196
CCRID; 1101RAT-PUMC000219
CCRID; 3101RATGNR5
CCRID; 4201RAT-CCTCC00606
Lonza; 1016
Anatomy/cell type resources BTO; BTO:0001879
Chemistry resources ChEMBL-Cells; CHEMBL3307653
ChEMBL-Targets; CHEMBL614576
PubChem_Cell_line; CVCL_0286
Encyclopedic resources Wikidata; Q9363821
Gene expression databases GEO; GSM1513690
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number27