ID   HMEC-1
AC   CVCL_0307
SY   Hmec-1; HMEC1; CDC/EU.HMEC-1; Human Microvascular Endothelial Cell line-1
DR   BTO; BTO:0002828
DR   EFO; EFO_0005383
DR   MCCL; MCC:0000200
DR   ATCC; CRL-3243
DR   ChEMBL-Cells; CHEMBL4295409
DR   ChEMBL-Targets; CHEMBL4296433
DR   CLS; 304064
DR   Lonza; 736
DR   PubChem_Cell_line; CVCL_0307
DR   Wikidata; Q54889921
RX   Patent=WO1992017569A1;
RX   PubMed=1361507;
RX   PubMed=12453433;
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-159.html
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-10636.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Foreskin, skin, dermis; UBERON=UBERON_0001471+UBERON_0002067.
CC   Cell type: Endothelial cell; CL=CL_0000115.
ST   Source(s): ATCC
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D5S818: 12
ST   D7S820: 8,10
ST   TH01: 7
ST   TPOX: 8,11
ST   vWA: 15,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   <1M
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 21
//
RX   Patent=WO1992017569A1;
RA   Ades E.W., Lawley T.J., Candal F.J.;
RT   "Immortalization of endothelial cells.";
RL   Patent number WO1992017569A1, 15-Oct-1992.
//
RX   PubMed=1361507; DOI=10.1111/1523-1747.ep12613748;
RA   Ades E.W., Candal F.J., Swerlick R.A., George V.G., Summers S.,
RA   Bosse D.C., Lawley T.J.;
RT   "HMEC-1: establishment of an immortalized human microvascular
RT   endothelial cell line.";
RL   J. Invest. Dermatol. 99:683-690(1992).
//
RX   PubMed=12453433; DOI=10.1006/mvre.2002.2434;
RA   Unger R.E., Krump-Konvalinkova V., Peters K., Kirkpatrick C.J.;
RT   "In vitro expression of the endothelial phenotype: comparative study
RT   of primary isolated cells and cell lines, including the novel cell
RT   line HPMEC-ST1.6R.";
RL   Microvasc. Res. 64:384-397(2002).
//