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Cellosaurus HNE-1 (CVCL_0308)

Cell line name HNE-1
Synonyms HNE1
Accession CVCL_0308
Resource Identification Initiative To cite this cell line use: HNE-1 (RRID:CVCL_0308)
Comments Problematic cell line: Possibly contaminated. The STR profile is very similar to that of the HeLa cell line and almost identical to that of HNE-2 (Cellosaurus=CVCL_FA07).
Virology: EBV-negative in established line.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptome analysis by RNAseq.
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=18196576; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,23
D3S135815,18
D5S81811,12
D7S82010,12
D8S117912,16 (PubMed=18196576)
12,17 (PubMed=25877200)
D13S31710,12,13.3
D16S5399,10 (PubMed=18196576)
9,10,11 (PubMed=25877200)
D18S5113,16
D19S43313
D21S1127,30
FGA18,21
Penta D9,12
Penta E17,20
TH016,7,9 (PubMed=18196576)
6,9 (PubMed=25877200)
TPOX8,12
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=2556716; DOI=10.1073/pnas.86.23.9524
Glaser R., Zhang H.-Y., Yao K.-T., Zhu H.-C., Wang F.-X., Li G.-Y., Wen D.-S., Li Y.-P.
Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas.
Proc. Natl. Acad. Sci. U.S.A. 86:9524-9528(1989)

PubMed=18196576; DOI=10.1002/ijc.23374
Chan S.Y.-Y., Choy K.-W., Tsao S.-W., Tao Q., Tang T., Chung G.T.-Y., Lo K.-W.
Authentication of nasopharyngeal carcinoma tumor lines.
Int. J. Cancer 122:2169-2171(2008)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

CLPUB00484
Xu Z.-H., Sun W.-W., Hang J.-B., Gao B.-L., Hu J.-A.
RNA-seq identified a novel functional MET fusion in head and neck cancer 5-8F cell line.
Int. J. Clin. Exp. Pathol. 9:8308-8317(2016)

Cross-references
Cell line databases/resources MCCL; MCC:0000201
Anatomy/cell type resources BTO; BTO:0006135
Biological sample resources BioSample; SAMN03472440
Encyclopedic resources Wikidata; Q54890030
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19