ID   HT22
AC   CVCL_0321
SY   HT-22
DR   BTO; BTO:0003037
DR   MCCL; MCC:0000214
DR   ChEMBL-Cells; CHEMBL3307590
DR   ChEMBL-Targets; CHEMBL614316
DR   Lonza; 248
DR   Millipore; SCC129
DR   PRIDE; PXD001597
DR   Wikidata; Q54896579
RX   PubMed=7953717;
RX   PubMed=9292733;
RX   PubMed=19135458;
RX   PubMed=26227174;
WW   http://salkinnovations.testtechnologypublisher.com/technology/7060
WW   http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-569.html
CC   Characteristics: Highly sensitive to glutamate and is therefore used to study glutamate-induced toxicity in neuronal cells.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [tsA58].
CC   Omics: Secretome proteome analysis.
OX   NCBI_TaxID=10090; ! Mus musculus
HI   CVCL_U378 ! HT4
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 07-09-18; Version: 13
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RX   PubMed=7953717; DOI=10.1016/0006-8993(94)90334-4;
RA   Davis J.B., Maher P.;
RT   "Protein kinase C activation inhibits glutamate-induced cytotoxicity
RT   in a neuronal cell line.";
RL   Brain Res. 652:169-173(1994).
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RX   PubMed=9292733; DOI=10.1016/S0896-6273(00)80953-8;
RA   Li Y., Maher P., Schubert D.;
RT   "A role for 12-lipoxygenase in nerve cell death caused by glutathione
RT   depletion.";
RL   Neuron 19:453-463(1997).
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RX   PubMed=19135458; DOI=10.1016/j.lfs.2008.12.008;
RA   Liu J., Li L., Suo W.Z.;
RT   "HT22 hippocampal neuronal cell line possesses functional cholinergic
RT   properties.";
RL   Life Sci. 84:267-271(2009).
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RX   PubMed=26227174; DOI=10.1002/pmic.201400623;
RA   Woo J.-M., Han D.-H., Park J.-H., Kim S.-J., Kim Y.-S.;
RT   "In-depth characterization of the secretome of mouse CNS cell lines by
RT   LC-MS/MS without prefractionation.";
RL   Proteomics 15:3617-3622(2015).
//