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Cellosaurus HuT78B1 (CVCL_0325)

[Text version]
Cell line name HuT78B1
Synonyms HUT78B1; HUT78-B1
Accession CVCL_0325
Resource Identification Initiative To cite this cell line use: HuT78B1 (RRID:CVCL_0325)
Comments Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene deletion; HGNC; 7208; MPDZ; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Sezary syndrome (NCIt: C3366)
Sezary syndrome (ORDO: Orphanet_3162)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0337 (HuT 78)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=8598453; DOI=10.4049/jimmunol.156.1.13
Cascino I., Papoff G., De Maria R., Testi R., Ruberti G.
Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis.
J. Immunol. 156:13-17(1996)

PubMed=15161037
Meli M., Tolomeo M., D'Alessandro N., Grimaudo S., Notarbartolo M., Papoff G., Ruberti G., Rausa L., Dusonchet L.
Resistance to gemcitabine in a lymphoma cell line resistant to Fas-mediated apoptosis.
Anticancer Res. 24:851-857(2004)

Cross-references
Cell line databases/resources MCCL; MCC:0000218
cancercelllines; CVCL_0325
Encyclopedic resources Wikidata; Q54896927
Polymorphism and mutation databases Cosmic; 2765584
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19