Home  |  Contact

Cellosaurus IMR-90 (CVCL_0347)

[Text version]

Cell line name IMR-90
Synonyms IMR 90; IMR90; Institute for Medical Research-90; I90
Accession CVCL_0347
Resource Identification Initiative To cite this cell line use: IMR-90 (RRID:CVCL_0347)
Comments Part of: ENCODE project common cell types; tier 2.
Part of: International Histocompatibility Workshop cell lines.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Omics: Deep proteome analysis.
Omics: DNA methylation analysis.
Omics: Genome sequenced.
Omics: H2A.Z; ChIP-seq epigenome analysis.
Omics: H2AK5ac ChIP-seq epigenome analysis.
Omics: H2AK9ac ChIP-seq epigenome analysis.
Omics: H2BK120ac ChIP-seq epigenome analysis.
Omics: H2BK12ac ChIP-seq epigenome analysis.
Omics: H2BK15ac ChIP-seq epigenome analysis.
Omics: H2BK20ac ChIP-seq epigenome analysis.
Omics: H2BK5ac ChIP-seq epigenome analysis.
Omics: H3K14ac ChIP-seq epigenome analysis.
Omics: H3K18ac ChIP-seq epigenome analysis.
Omics: H3K23ac ChIP-seq epigenome analysis.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K36me3 ChIP-seq epigenome analysis.
Omics: H3K4ac ChIP-seq epigenome analysis.
Omics: H3K4me1 ChIP-seq epigenome analysis.
Omics: H3K4me2 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: H3K56ac ChIP-seq epigenome analysis.
Omics: H3K79me1 ChIP-seq epigenome analysis.
Omics: H3K79me2 ChIP-seq epigenome analysis.
Omics: H3K9ac ChIP-seq epigenome analysis.
Omics: H3K9me1 ChIP-seq epigenome analysis.
Omics: H3K9me3 ChIP-seq epigenome analysis.
Omics: H4K20me1 ChIP-seq epigenome analysis.
Omics: H4K5ac ChIP-seq epigenome analysis.
Omics: H4K8ac ChIP-seq epigenome analysis.
Omics: H4K91ac ChIP-seq epigenome analysis.
Omics: SNP array analysis.
Misspelling: IRM-90; Occasionally.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_M230 (AG03204)CVCL_3874 (IDH4)CVCL_RM51 (IM23-16)
CVCL_RM52 (IM23-9)CVCL_RM53 (IM25-2)CVCL_2963 (IMR-90-40)
CVCL_2964 (IMR-90-50)CVCL_6269 (IMR-90-SV)CVCL_HA48 (IMR-90/GFPdeltaRaf-1[YY]:ER)
CVCL_C434 (IPS(IMR90)-1)CVCL_C435 (IPS(IMR90)-2)CVCL_C436 (IPS(IMR90)-3)
CVCL_C437 (IPS(IMR90)-4)CVCL_U243 (ITV)CVCL_V155 (MSUH-001)
CVCL_JW74 (YZ1)
Sex of cell Female
Age at sampling 16FW
Category Finite cell line
STR profile Source(s): ATCC; JCRB; KCLB; PubMed=11416159

Markers:
AmelogeninX
CSF1PO11,13
D3S135814,15
D5S81812,13
D7S8209,12
D8S117913,14
D13S31711,13
D16S53910,13
D18S5117
D21S1130.2,31
FGA25,26
TH018,9.3 (ATCC; KCLB; PubMed=11416159)
8,10 (JCRB)
TPOX8,9
vWA16,19

Run an STR similarity search on this cell line
Web pages http://genome.ucsc.edu/ENCODE/protocols/cell/human/IMR90_Stam_protocol.pdf
http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/i/cell-lines-detail-246.html
Publications

PubMed=841339; DOI=10.1126/science.841339
Nichols W.W., Murphy D.G., Cristofalo V.J., Toji L.H., Greene A.E., Dwight S.A.
Characterization of a new human diploid cell strain, IMR-90.
Science 196:60-63(1977)

PubMed=211143
Friedman H.M., Koropchak C.
Comparison of WI-38, MRC-5, and IMR-90 cell strains for isolation of viruses from clinical specimens.
J. Clin. Microbiol. 7:368-371(1978)

PubMed=738322; DOI=10.1080/03610737808257154
Das N.K., Murphy D.G.
National Institute on Aging cell-line repository.
Exp. Aging Res. 4:321-331(1978)

PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222
Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.
Cultured cell lines for research on pulmonary physiology available through the American Type Culture Collection.
Am. Rev. Respir. Dis. 125:222-232(1982)

PubMed=1574572; DOI=10.2307/3578273
Dunphy E.J., Beckett M.A., Thompson L.H., Weichselbaum R.R.
Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Radiat. Res. 130:166-170(1992)

CLPUB00499
Beiswanger C.
A brief history of IMR-90.
Cell Collections 2004:5-6(2004)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22108792; DOI=10.1038/msb.2011.84
Munoz J., Low T.Y., Kok Y.J., Chin A., Frese C.K., Ding V., Choo A., Heck A.J.R.
The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells.
Mol. Syst. Biol. 7:550-550(2011)

PubMed=23325432; DOI=10.1101/gr.147942.112
Varley K.E., Gertz J., Bowling K.M., Parker S.L., Reddy T.E., Pauli-Behn F., Cross M.K., Williams B.A., Stamatoyannopoulos J.A., Crawford G.E., Absher D.M., Wold B.J., Myers R.M.
Dynamic DNA methylation across diverse human cell lines and tissues.
Genome Res. 23:555-567(2013)

Cross-references
Cell line collections AddexBio; P0016019/4978
ATCC; CCL-186
ATCC; CRL-7931 - Discontinued
BCRC; 60204
BCRJ; 0118
Coriell; I90-10
Coriell; I90-15
Coriell; I90-19
Coriell; I90-24
Coriell; I90-26
Coriell; I90-33
Coriell; I90-40
Coriell; I90-52 - Discontinued
Coriell; I90-53
Coriell; I90-78 - Discontinued
Coriell; I90-79
Coriell; I90-83
ECACC; 85020204
IZSLER; BS CL 107
JCRB; JCRB0516
JCRB; JCRB9054
KCLB; 10186
Cell line databases/resources CLDB; cl2889
CLDB; cl2890
IPD-IMGT/HLA; 11782
Lonza; 745
Ontologies BTO; BTO:0001229
CLO; CLO_0006951
CLO; CLO_0029276
CLO; CLO_0029279
CLO; CLO_0029284
CLO; CLO_0029291
CLO; CLO_0029294
CLO; CLO_0029328
CLO; CLO_0029330
CLO; CLO_0029331
CLO; CLO_0029332
CLO; CLO_0029336
EFO; EFO_0001196
MCCL; MCC:0000243
Biological sample resources 4DN; 4DNSRI51KRED
4DN; 4DNSRXXGU3CH
BioSample; SAMN03471461
BioSample; SAMN03472414
ENCODE; ENCBS007TVF
ENCODE; ENCBS048GPK
ENCODE; ENCBS048TNH
ENCODE; ENCBS073JZM
ENCODE; ENCBS192DLO
ENCODE; ENCBS357USI
ENCODE; ENCBS364NFD
ENCODE; ENCBS368ENC
ENCODE; ENCBS369ENC
ENCODE; ENCBS370ENC
ENCODE; ENCBS371ENC
ENCODE; ENCBS371NWL
ENCODE; ENCBS372ENC
ENCODE; ENCBS373ENC
ENCODE; ENCBS379ENC
ENCODE; ENCBS410ENC
ENCODE; ENCBS411ENC
ENCODE; ENCBS412ENC
ENCODE; ENCBS412SDE
ENCODE; ENCBS413ENC
ENCODE; ENCBS414ENC
ENCODE; ENCBS415ENC
ENCODE; ENCBS416ENC
ENCODE; ENCBS460CLV
ENCODE; ENCBS472JFT
ENCODE; ENCBS486FIC
ENCODE; ENCBS562LLK
ENCODE; ENCBS598YLQ
ENCODE; ENCBS648SCY
ENCODE; ENCBS683AVF
ENCODE; ENCBS754TWW
ENCODE; ENCBS780OTZ
ENCODE; ENCBS981IKS
ENCODE; ENCBS981UBX
ENCODE; ENCBS982GUC
ENCODE; ENCBS992YMT
Chemistry resources ChEMBL-Cells; CHEMBL3307985
ChEMBL-Targets; CHEMBL612577
Gene expression databases GEO; GSM432687
GEO; GSM432688
GEO; GSM432689
GEO; GSM432690
GEO; GSM432691
GEO; GSM432692
GEO; GSM438363
GEO; GSM438364
GEO; GSM468792
GEO; GSM468801
GEO; GSM469965
GEO; GSM469966
GEO; GSM469967
GEO; GSM469968
GEO; GSM469970
GEO; GSM469973
GEO; GSM469974
GEO; GSM469975
GEO; GSM521866
GEO; GSM521868
GEO; GSM521869
GEO; GSM521870
GEO; GSM521871
GEO; GSM521873
GEO; GSM521874
GEO; GSM521875
GEO; GSM521877
GEO; GSM521878
GEO; GSM521879
GEO; GSM521880
GEO; GSM521881
GEO; GSM521883
GEO; GSM521884
GEO; GSM521885
GEO; GSM521886
GEO; GSM521887
GEO; GSM521889
GEO; GSM521890
GEO; GSM521892
GEO; GSM521893
GEO; GSM521894
GEO; GSM521895
GEO; GSM521897
GEO; GSM521898
GEO; GSM521899
GEO; GSM521900
GEO; GSM521901
GEO; GSM521902
GEO; GSM521903
GEO; GSM521904
GEO; GSM521906
GEO; GSM521907
GEO; GSM521908
GEO; GSM521909
GEO; GSM521911
GEO; GSM521912
GEO; GSM521913
GEO; GSM521914
GEO; GSM521915
GEO; GSM521917
GEO; GSM521918
GEO; GSM521919
GEO; GSM521921
GEO; GSM521922
GEO; GSM521923
GEO; GSM521924
GEO; GSM521925
GEO; GSM521926
GEO; GSM521927
GEO; GSM521928
GEO; GSM521929
GEO; GSM521930
GEO; GSM521931
GEO; GSM521932
GEO; GSM521933
GEO; GSM530665
GEO; GSM530666
GEO; GSM541279
GEO; GSM541280
GEO; GSM604470
GEO; GSM604471
GEO; GSM723024
GEO; GSM752986
GEO; GSM752987
GEO; GSM818007
GEO; GSM818008
GEO; GSM818012
GEO; GSM818013
GEO; GSM818017
GEO; GSM827198
GEO; GSM832837
GEO; GSM832838
GEO; GSM862724
GEO; GSM892307
GEO; GSM909321
GEO; GSM909338
GEO; GSM909339
GEO; GSM923447
GEO; GSM927235
GEO; GSM935403
GEO; GSM935404
GEO; GSM935513
GEO; GSM935519
GEO; GSM935624
GEO; GSM942307
GEO; GSM942928
GEO; GSM959044
GEO; GSM1003612
GEO; GSM1003613
GEO; GSM1003614
GEO; GSM1003615
GEO; GSM1003623
GEO; GSM1008586
GEO; GSM1055800
GEO; GSM1055801
GEO; GSM1068140
GEO; GSM1068141
GEO; GSM1154021
GEO; GSM1154022
GEO; GSM1154023
GEO; GSM1154024
GEO; GSM1186664
GEO; GSM1296454
GEO; GSM1463270
Other Wikidata; Q54897669
Proteomic databases PRIDE; PXD000134
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number24