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Cellosaurus J2E (CVCL_0355)

[Text version]

Cell line name J2E
Synonyms J2E-1
Accession CVCL_0355
Resource Identification Initiative To cite this cell line use: J2E (RRID:CVCL_0355)
Comments Characteristics: Differentiates and synthesizes hemoglobin following exposure to EPO.
Transformant: Recombinant retrovirus J2.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CBA.
Hierarchy Children:
CVCL_5984 (J2E-NR)
Sex of cell Sex unspecified
Age at sampling 12FD
Category Transformed cell line

PubMed=2847163; DOI=10.1073/pnas.85.22.8506
Klinken S.P., Nicola N.A., Johnson G.R.
In vitro-derived leukemic erythroid cell lines induced by a raf- and myc-containing retrovirus differentiate in response to erythropoietin.
Proc. Natl. Acad. Sci. U.S.A. 85:8506-8510(1988)

Klinken S.P., Nicola N.A.
Evolution of a mutant J2E erythroid cell line which does not respond to erythropoietin.
Leukemia 4:24-28(1990)

PubMed=8631947; DOI=10.1074/jbc.271.7.3453
Tilbrook P.A., Bittorf T., Busfield S.J., Chappell D., Klinken S.P.
Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin.
J. Biol. Chem. 271:3453-3459(1996)

Ontologies MCCL; MCC:0000249
Other Wikidata; Q54898464
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number7