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Cellosaurus K562YO (CVCL_0369)

[Text version]

Cell line name K562YO
Accession CVCL_0369
Resource Identification Initiative To cite this cell line use: K562YO (RRID:CVCL_0369)
Comments Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=7506674
Ogawa K., Tashima M., Toi T., Sawai H., Sawada H., Fujita J., Maruyama Y., Okuma M.
Inhibition of erythroid differentiation by stem cell factor in K562 cells expressing the c-kit gene.
Exp. Hematol. 22:45-51(1994)

PubMed=7534132
Ogawa K., Takeda Y., Tashima M., Sawai H., Toi T., Okazaki T., Sawada H., Maruyama Y., Okuma M.
High expression of c-kit in K562YO cells due to the prolonged half-life of its mRNA: the effects of modification with serine/threonine kinase signals.
Blood 85:1496-1503(1995)

Cross-references
Ontologies MCCL; MCC:0000263
Other Wikidata; Q54899422
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number13