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Cellosaurus K562YO (CVCL_0369)

[Text version]

Cell line name K562YO
Accession CVCL_0369
Resource Identification Initiative To cite this cell line use: K562YO (RRID:CVCL_0369)
Comments Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line

Ogawa K., Tashima M., Toi T., Sawai H., Sawada H., Fujita J., Maruyama Y., Okuma M.
Inhibition of erythroid differentiation by stem cell factor in K562 cells expressing the c-kit gene.
Exp. Hematol. 22:45-51(1994)

PubMed=7534132; DOI=10.1182/blood.V85.6.1496.bloodjournal8561496
Ogawa K., Takeda Y., Tashima M., Sawai H., Toi T., Okazaki T., Sawada H., Maruyama Y., Okuma M.
High expression of c-kit in K562YO cells due to the prolonged half-life of its mRNA: the effects of modification with serine/threonine kinase signals.
Blood 85:1496-1503(1995)

Ontologies MCCL; MCC:0000263
Other Wikidata; Q54899422
Entry history
Entry creation04-Apr-2012
Last entry update12-Mar-2020
Version number14