Cell line name | KNS-42 | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | KNS42 | ||||||||||||||||||
Accession | CVCL_0378 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: KNS-42 (RRID:CVCL_0378) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Population: Japanese. Doubling time: 48 hours (CelloPub=CLPUB00152; PubMed=19365568). Microsatellite instability: Stable (MSS) (Sanger). Omics: CNV analysis. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Brain; right frontoparietal lobe. | ||||||||||||||||||
Sequence variations | Heterozygous for BLM p.Ser186_Lys187delinsTer (c.557_559delCAA) (S186*) (ClinVar=VCV000005455) (CCLE; Cosmic-CLP).Homozygous for TP53 p.Arg342Ter (c.1024C>T) (ClinVar=VCV000182970) (CCLE; Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
| ||||||||||||||||||
Disease | Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
| ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 16Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; JCRB Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=2448680; DOI=10.2176/nmc.27.581 CLPUB00152 PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x PubMed=19365568; DOI=10.1371/journal.pone.0005209 PubMed=20164919; DOI=10.1038/nature08768 PubMed=22460905; DOI=10.1038/nature11003 PubMed=25628092; DOI=10.1038/bjc.2015.16 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=31978347; DOI=10.1016/j.cell.2019.12.023 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | BCRJ; 0295
JCRB; IFO50356 | ||||||||||||||||||
Cell line databases/resources | CCLE; KNS42_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00607 CGH-DB; 144-1 Cosmic-CLP; 907282 DepMap; ACH-000622 LINCS_LDP; LCL-1382 | ||||||||||||||||||
Ontologies | BTO; BTO:0005859
MCCL; MCC:0000273 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03472787
BioSample; SAMN10987931 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308538
ChEMBL-Targets; CHEMBL2366261 GDSC; 907282 PharmacoDB; KNS42_773_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM887229 GEO; GSM888303 GEO; GSM1669995 GEO; GSM2197880 GEO; GSM2197881 GEO; GSM2197882 GEO; GSM2197883 GEO; GSM2197884 GEO; GSM2197885 | ||||||||||||||||||
Other | Wikidata; Q54900250 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687573
Cosmic; 907282 Cosmic; 2367532 IARC_TP53; 21436 LiGeA; CCLE_847 Progenetix; CVCL_0378 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 12-Jan-2021 | ||||||||||||||||||
Version number | 28 |