Cell line name | Ku812 | ||||||||||||||||||||||||||||||||
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Synonyms | KU812; KU-812; KU.812; KU 812 | ||||||||||||||||||||||||||||||||
Accession | CVCL_0379 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: Ku812 (RRID:CVCL_0379) | ||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Part of: LL-100 blood cancer cell line panel. Population: Japanese. Doubling time: ~80-100 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Peripheral blood. | ||||||||||||||||||||||||||||||||
Sequence variations | Gene fusion; BCR-ABL1 (PubMed=15843827; DepMap).Homozygous for TP53 p.Lys132Arg (c.395A>G) (ClinVar=VCV000376625) (Cosmic-CLP). | ||||||||||||||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174) Chronic myeloid leukemia (ORDO: Orphanet_521) | ||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||
Age at sampling | 38Y | ||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP; DSMZ; ECACC; JCRB; PubMed=11416159; PubMed=25877200; RCB Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Web pages | http://www.cellresource.cn/fdetail.aspx?id=1698 | ||||||||||||||||||||||||||||||||
Publications | PubMed=3858609; DOI=10.1016/0145-2126(85)90060-8 PubMed=3332852; DOI=10.1016/S0950-3536(87)80037-9 PubMed=2540861; DOI=10.1182/blood.V73.7.2003.2003 DOI=10.11418/jtca1981.15.4_211 PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x PubMed=9644295; DOI=10.1159/000040837 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=15843827; DOI=10.1038/sj.leu.2403749 PubMed=16408098; DOI=10.1038/sj.leu.2404081 PubMed=20164919; DOI=10.1038/nature08768 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=22460905; DOI=10.1038/nature11003 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30285677; DOI=10.1186/s12885-018-4840-5 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=31160637; DOI=10.1038/s41598-019-44491-x | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Cell line collections | ATCC; CRL-2099
BCRC; 60502 BCRJ; 0261 DSMZ; ACC-378 ECACC; 90071807 JCRB; IFO50363 JCRB; JCRB0104 RCB; RCB0495 | ||||||||||||||||||||||||||||||||
Cell line databases/resources | CLDB; cl3070
CCLE; KU812_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCRID; 3131C0001000700189 Cell_Model_Passport; SIDM00308 CGH-DB; 9211-4 Cosmic-CLP; 907311 DepMap; ACH-000074 IGRhCellID; KU812 LINCS_LDP; LCL-1106 Lonza; 1207 | ||||||||||||||||||||||||||||||||
Ontologies | BTO; BTO:0000732
CLO; CLO_0007124 CLO; CLO_0007125 CLO; CLO_0050989 EFO; EFO_0002222 MCCL; MCC:0000274 | ||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN01821693
BioSample; SAMN01821733 BioSample; SAMN03472893 BioSample; SAMN10988528 | ||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308504
ChEMBL-Targets; CHEMBL613997 GDSC; 907311 PharmacoDB; KU812_795_2019 | ||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 ArrayExpress; E-MTAB-7721 ArrayExpress; E-MTAB-7722 GEO; GSM887244 GEO; GSM888318 GEO; GSM1374606 GEO; GSM1670011 | ||||||||||||||||||||||||||||||||
Other | Wikidata; Q54900693 | ||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 787498
Cosmic; 907311 Cosmic; 919119 Cosmic; 922163 Cosmic; 924052 Cosmic; 949096 Cosmic; 991560 Cosmic; 999778 Cosmic; 1012080 Cosmic; 1026568 Cosmic; 1067444 Cosmic; 1078716 Cosmic; 1519164 Cosmic; 2009518 IARC_TP53; 342 IARC_TP53; 21446 LiGeA; CCLE_172 Progenetix; CVCL_0379 | ||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||
Last entry update | 12-Jan-2021 | ||||||||||||||||||||||||||||||||
Version number | 32 |