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Cellosaurus L6 (CVCL_0385)

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Cell line name L6
Synonyms L-6; L-6 myoblast
Accession CVCL_0385
Resource Identification Initiative To cite this cell line use: L6 (RRID:CVCL_0385)
Comments Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Anecdotal: Called L6 by David Yaffe because he and Sara Neuman established the cell line during the Six-Day war in 1967 (PubMed=33117511).
Derived from sampling site: Skeletal muscle; myoblast.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Hierarchy Children:
CVCL_0P25 (L6-GLUT-4myc)CVCL_3834 (L6.C10)CVCL_3835 (L6.C11)
CVCL_3836 (L6.G8)CVCL_3837 (L6.G8.C5)CVCL_C569 (L6A4)
CVCL_3387 (L6C5)CVCL_C570 (L6C9)CVCL_UI07 (L6Cl1)
CVCL_UI08 (L6Cl2)CVCL_UI09 (L6Cl5)CVCL_UI10 (L6Cl6)
CVCL_0386 (L6E9)CVCL_3388 (L6H2)CVCL_6F18 (L6J1)
CVCL_C565 (L6TG)
Sex of cell Male
Age at sampling 1D
Category Transformed cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-130.html

PubMed=5245982; DOI=10.1073/pnas.61.2.477
Yaffe D.
Retention of differentiation potentialities during prolonged cultivation of myogenic cells.
Proc. Natl. Acad. Sci. U.S.A. 61:477-483(1968)

PubMed=5481965; DOI=10.1016/S0012-1606(70)80004-5
Richler C., Yaffe D.
The in vitro cultivation and differentiation capacities of myogenic cell lines.
Dev. Biol. 23:1-22(1970)

PubMed=7297605; DOI=10.1016/0014-4827(81)90032-X
Parfett C.L.J., Jamieson J.C., Wright J.A.
A correlation between loss of fusion potential and defective formation of mannose-linked lipid intermediates in independent concanavalin A-resistant myoblast cell lines.
Exp. Cell Res. 136:1-14(1981)

PubMed=1311324; DOI=10.1016/S0021-9258(18)42923-7
Mitsumoto Y., Klip A.
Development regulation of the subcellular distribution and glycosylation of GLUT1 and GLUT4 glucose transporters during myogenesis of L6 muscle cells.
J. Biol. Chem. 267:4957-4962(1992)

PubMed=10484371; DOI=10.1152/ajpendo.1999.277.3.E572
Ueyama A., Yaworsky K.L., Wang Q., Ebina Y., Klip A.
GLUT-4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity.
Am. J. Physiol. 277:E572-E578(1999)

PubMed=33117511; DOI=10.4081/ejtm.2020.9306
Yablonka-Reuveni Z., Stockdale F.E., Nudel U., Israeli D., Blau H.M., Shainberg A., Neuman S., Kessler-Icekson G., Krull E.M., Paterson B., Fuchs O.S., Greenberg D., Sarig R., Halevy O., Ozawa E., Katcoff D.J.
Farewell to professor David Yaffe -- A pillar of the myogenesis field.
Eur. J. Transl. Myol. 30:9306.1-9306.16(2020)

Cell line collections ATCC; CRL-1458
BCRJ; 0141
JCRB; IFO50364
KCLB; 21458
Kerafast; ESK201-FP
Cell line databases/resources CLDB; cl3142
CLDB; cl5220
CCRID; 1101RAT-PUMC000192
Lonza; 927
Ontologies BTO; BTO:0002809
CLO; CLO_0007203
MCCL; MCC:0000280
Chemistry resources ChEMBL-Cells; CHEMBL3308469
ChEMBL-Targets; CHEMBL614793
Other Wikidata; Q54901051
Proteomic databases PRIDE; PXD002557
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number23