ID   LLC-PK1
AC   CVCL_0391
AS   CVCL_K238
SY   LLC-PK(1); LLC-PK-1; LLC PK-1; LLc-PK1; LLC PK1; LLCPK1; Lilly Laboratories Culture-Porcine Kidney 1
DR   BTO; BTO:0000760
DR   CLO; CLO_0007331
DR   MCCL; MCC:0000286
DR   CLDB; cl3221
DR   CLDB; cl5221
DR   ATCC; CL-101
DR   ATCC; CRL-1392
DR   BCRC; 60080
DR   BCRJ; 0147
DR   CCRID; 1101SWI-PUMC000111
DR   CCRID; 4201SWI-CCTCC00612
DR   ChEMBL-Cells; CHEMBL3307655
DR   ChEMBL-Targets; CHEMBL614577
DR   CLS; 607264
DR   DSMZ; ACC-637
DR   DSMZCellDive; ACC-637
DR   ECACC; 86121112
DR   IZSLER; BS CL 111
DR   JCRB; JCRB0060
DR   Lonza; 844
DR   MeSH; D018374
DR   PRIDE; PXD007891
DR   TOKU-E; 2208
DR   Wikidata; Q28334936
RX   Patent=US3904480;
RX   PubMed=828141;
RX   PubMed=8097873;
RX   PubMed=14449902;
RX   PubMed=19508353;
RX   PubMed=20555413;
WW   https://www.atcc.org/en/support/technical-support/faqs/atcc-cl-101-vs-atcc-cl-101-1
WW   https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/llcpk1/llcpk1cells.html
WW   https://www.olympus-lifescience.com/de/microscope-resource/primer/techniques/fluorescence/gallery/cells/epithelialindex/
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-150.html
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CL-101.
CC   Doubling time: ~24 hours (DSMZ).
CC   Discontinued: ATCC; CRL-1392; true.
CC   Derived from sampling site: Kidney.
CC   Breed/subspecies: Hampshire.
OX   NCBI_TaxID=9823; ! Sus scrofa
SX   Male
AG   3-4W
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 23-06-22; Version: 27
//
RX   Patent=US3904480;
RA   Hull R.N., Huseby R.M.;
RT   "Enhanced production of plasminogen activator.";
RL   Patent number US3904480, 09-Sep-1975.
//
RX   PubMed=828141; DOI=10.1007/BF02797469;
RA   Hull R.N., Cherry W.R., Weaver G.W.;
RT   "The origin and characteristics of a pig kidney cell strain, LLC-PK1.";
RL   In Vitro 12:670-677(1976).
//
RX   PubMed=8097873; DOI=10.1023/a:1018954204094;
RA   Hori R., Okuda M., Ohishi Y., Yasuhara M., Inui K.-I., Takano M.;
RT   "Decreased cellular toxicity of neomycin in a clonal cell line
RT   isolated from LLC-PK1.";
RL   Pharm. Res. 10:573-576(1993).
//
RX   PubMed=14449902;
RA   Hull R.N., Tritch O.J.;
RT   "Characterization of cell strains by viral susceptibility.";
RL   Natl. Cancer Inst. Monogr. 7:161-172(1962).
//
RX   PubMed=19508353; DOI=10.1111/j.1744-313X.2009.00853.x;
RA   Ho C.S., Franzo-Romain M.H., Lee Y.J., Lee J.H., Smith D.M.;
RT   "Sequence-based characterization of swine leucocyte antigen alleles in
RT   commercially available porcine cell lines.";
RL   Int. J. Immunogenet. 36:231-234(2009).
//
RX   PubMed=20555413; DOI=10.1139/y10-023;
RA   Gunness P., Aleksa K., Kosuge K., Ito S., Koren G.;
RT   "Comparison of the novel HK-2 human renal proximal tubular cell line
RT   with the standard LLC-PK1 cell line in studying drug-induced
RT   nephrotoxicity.";
RL   Can. J. Physiol. Pharmacol. 88:448-455(2010).
//