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Cellosaurus LN-308 (CVCL_0394)

Cell line name LN-308
Synonyms LN 308; LN308; LNZ-308; LNZ 308; LNZ308; LN-Z308
Accession CVCL_0394
Resource Identification Initiative To cite this cell line use: LN-308 (RRID:CVCL_0394)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 30 hours (PubMed=25984343).
Omics: Array-based CGH.
Omics: shRNA library screening.
Disease Astrocytoma (NCIt: C60781)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): PubMed=22570425

Penta D9,11
Penta E7,10

PubMed=2990147; DOI=10.1007/BF00688585
Studer A., de Tribolet N., Diserens A.-C., Gaide A.-C., Matthieu J.-M., Carrel S., Stavrou D.
Characterization of four human malignant glioma cell lines.
Acta Neuropathol. 66:208-217(1985)

Li H., Hamou M.-F., de Tribolet N., Jaufeerally R., Hofmann M., Diserens A.-C., Van Meir E.G.
Variant CD44 adhesion molecules are expressed in human brain metastases but not in glioblastomas.
Cancer Res. 53:5345-5349(1993)

PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x
Ishii N., Maier D., Merlo A., Tada M., Sawamura Y., Diserens A.-C., Van Meir E.G.
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.
Brain Pathol. 9:469-479(1999)

PubMed=11351043; DOI=10.1038/labinvest.3780280
Hui A.B.-Y., Lo K.-W., Yin X.-L., Poon W.-S., Ng H.-K.
Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative genomic hybridization.
Lab. Invest. 81:717-723(2001)

PubMed=20504876; DOI=10.1093/neuonc/noq051
Berger B., Capper D., Lemke D., Pfenning P.-N., Platten M., Weller M., von Deimling A., Wick W., Weiler M.
Defective p53 antiangiogenic signaling in glioblastoma.
Neuro-oncol. 12:894-907(2010)

PubMed=22570425; DOI=10.1093/neuonc/nos072
Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K., Hamou M.-F., Delorenzi M., Hegi M.E.
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

Cell line databases/resources CCLE; LNZ308_CENTRAL_NERVOUS_SYSTEM
Ontologies BTO; BTO:0004457
MCCL; MCC:0000289
Other Wikidata; Q54902775
Polymorphism and mutation databases Cosmic; 849863
Cosmic; 2367499
Cosmic; 2516023