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Cellosaurus M059K (CVCL_0401)

[Text version]

Cell line name M059K
Accession CVCL_0401
Resource Identification Initiative To cite this cell line use: M059K (RRID:CVCL_0401)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep quantitative phosphoproteome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.16
Native American0
East Asian, North2.3
East Asian, South0
South Asian0
European, North69.38
European, South28.16
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0400 ! M059J
Sex of cell Male
Age at sampling 33Y
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135814,15
D5S81811,12
D7S82010
D8S117915
D13S31714
D16S53910,12
D18S5115,19
D21S1130,31.2
FGA20,26
Penta D12,13
Penta E7,15
TH019.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=8316628; DOI=10.2307/3578196
Allalunis-Turner M.J., Barron G.M., Day R.S. III, Dobler K.D., Mirzayans R.
Isolation of two cell lines from a human malignant glioma specimen differing in sensitivity to radiation and chemotherapeutic drugs.
Radiat. Res. 134:349-354(1993)

PubMed=18077418; DOI=10.1073/pnas.0707579104
Stokes M.P., Rush J., Macneill J., Ren J.M., Sprott K., Nardone J., Yang V., Beausoleil S.A., Gygi S.P., Livingstone M., Zhang H., Polakiewicz R.D., Comb M.J.
Profiling of UV-induced ATM/ATR signaling pathways.
Proc. Natl. Acad. Sci. U.S.A. 104:19855-19860(2007)

PubMed=21406405; DOI=10.1158/0008-5472.CAN-10-3112
Grzmil M., Morin P. Jr., Lino M.M., Merlo A., Frank S., Wang Y., Moncayo G., Hemmings B.A.
MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-beta signaling pathway in human glioblastoma.
Cancer Res. 71:2392-2402(2011)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ATCC; CRL-2365
BCRC; 60381
Cell line databases/resources CCLE; M059K_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00639
LINCS_LDP; LCL-1362
Ontologies CLO; CLO_0007446
EFO; EFO_0006451
MCCL; MCC:0000295
Biological sample resources BioSample; SAMN03473046
Gene expression databases ArrayExpress; E-MTAB-2706
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM887286
GEO; GSM888361
GEO; GSM1374641
GEO; GSM1670071
Other Wikidata; Q54903416
Polymorphism and mutation databases Cosmic; 897445
Cosmic; 1237543
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number20