ID   M7TS90
AC   CVCL_0404
DR   MCCL; MCC:0000298
DR   cancercelllines; CVCL_0404
DR   Wikidata; Q54903649
RX   PubMed=11980662;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 19
//
RX   PubMed=11980662;
RA   Longley D.B., Boyer J., Allen W.L., Latif T., Ferguson P.R.,
RA   Maxwell P.J., McDermott U., Lynch M., Harkin D.P., Johnston P.G.;
RT   "The role of thymidylate synthase induction in modulating
RT   p53-regulated gene expression in response to 5-fluorouracil and
RT   antifolates.";
RL   Cancer Res. 62:2644-2649(2002).
//