ID   MAIL8-3
AC   CVCL_0406
SY   MAIL8
DR   MCCL; MCC:0000300
DR   Wikidata; Q54903976
RX   PubMed=15701651;
RX   PubMed=16964285;
CC   Transfected with: HGNC; 16412; NLRC4 (with p.Leu152_Ala1024del, CARD domain, C12N2 construct).
CC   Transfected with: HGNC; 5331; NOD2 (with p.Met1_Ala216del, NACHT+LRR domains, C12N2 construct).
CC   Transfected with: HGNC; 16608; PYCARD.
CC   Transfected with: UniProtKB; P42212; GFP.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 11
//
RX   PubMed=15701651; DOI=10.1074/jbc.M412284200;
RA   Hasegawa M., Imamura R., Kinoshita T., Matsumoto N., Masumoto J.,
RA   Inohara N., Suda T.;
RT   "ASC-mediated NF-kappaB activation leading to interleukin-8 production
RT   requires caspase-8 and is inhibited by CLARP.";
RL   J. Biol. Chem. 280:15122-15130(2005).
//
RX   PubMed=16964285; DOI=10.1038/sj.onc.1209965;
RA   Hasegawa M., Kawase K., Inohara N., Imamura R., Yeh W.-C.,
RA   Kinoshita T., Suda T.;
RT   "Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type
RT   II cells.";
RL   Oncogene 26:1748-1756(2007).
//