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Cellosaurus MCF7mp53 (CVCL_0415)

[Text version]

Cell line name MCF7mp53
Synonyms MCF7 mp53; MCF-7-mp53; MCF-7mp53
Accession CVCL_0415
Resource Identification Initiative To cite this cell line use: MCF7mp53 (RRID:CVCL_0415)
Comments Transfected with: HGNC; 11998; TP53.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=11278253; DOI=10.1074/jbc.C100025200
Gupta S., Radha V., Furukawa Y., Swarup G.
Direct transcriptional activation of human caspase-1 by tumor suppressor p53.
J. Biol. Chem. 276:10585-10588(2001)

Cross-references
Ontologies MCCL; MCC:0000311
Other Wikidata; Q54904475
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number13