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Cellosaurus MDCK-II (CVCL_0424)

Cell line name MDCK-II
Synonyms MDCK II; MDCKII; MDCK2; MDCK-2; MDCK Type II; MDCKII-WT
Accession CVCL_0424
Resource Identification Initiative To cite this cell line use: MDCK-II (RRID:CVCL_0424)
Comments Group: Vaccine production cell line.
Omics: Deep proteome analysis.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel.
Hierarchy Parent: CVCL_0422 (MDCK)
Children:
CVCL_S586 (MDCK-MDR1)CVCL_X022 (MDCK-MRP2)CVCL_VR40 (MDCKII-LE)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022
Karger A., Bettin B., Lenk M., Mettenleiter T.C.
Rapid characterisation of cell cultures by matrix-assisted laser desorption/ionisation mass spectrometric typing.
J. Virol. Methods 164:116-121(2010)

PubMed=21766308; DOI=10.1002/jps.22674
Di L., Whitney-Pickett C., Umland J.P., Zhang H., Zhang X., Gebhard D.F., Lai Y., Federico J.J. III, Davidson R.E., Smith R., Reyner E.L., Lee C., Feng B., Rotter C., Varma M.V., Kempshall S., Fenner K., El-Kattan A.F., Liston T.E., Troutman M.D.
Development of a new permeability assay using low-efflux MDCKII cells.
J. Pharm. Sci. 100:4974-4985(2011)

PubMed=21982418; DOI=10.1186/1471-2121-12-43
Dukes J.D., Whitley P., Chalmers A.D.
The MDCK variety pack: choosing the right strain.
BMC Cell Biol. 12:43-43(2011)

PubMed=24975811; DOI=10.1016/j.vaccine.2014.06.045
Donis R.O., Chen I.-M., Davis C.T., Foust A., Hossain M.J., Johnson A., Klimov A., Loughlin R., Xu X., Tsai T., Blayer S., Trusheim H., Colegate T., Fox J., Taylor B., Hussain A., Barr I., Baas C., Louwerens J., Geuns E., Lee M.-S., Venhuizen O., Neumeier E., Ziegler T.
Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturing.
Vaccine 32:6583-6590(2014)

Cross-references
Cell line collections AddexBio; P0014001/82
CCLV; CCLV-RIE 1061
ECACC; 00062107
Cell line databases/resources Lonza; 811
Ontologies BTO; BTO:0004607
MCCL; MCC:0000321
Chemistry resources ChEMBL-Cells; CHEMBL3308862
Other Wikidata; Q54904781
Proteomic databases PRIDE; PXD001130