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Cellosaurus MIN6 (CVCL_0431)

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Cell line name MIN6
Synonyms Min6; MIN-6; Mouse INsulinoma 6
Accession CVCL_0431
Resource Identification Initiative To cite this cell line use: MIN6 (RRID:CVCL_0431)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Cell surface proteome.
Omics: Endoplasmic reticulum proteome analysis.
Disease Mouse insulinoma (NCIt: C34053)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_4372 (MIN6-m14)CVCL_4371 (MIN6-m9)CVCL_D686 (MIN6N8)
Age at sampling 13W
Category Transformed cell line
Web pages http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-93.html

PubMed=2163307; DOI=10.1210/endo-127-1-126
Miyazaki J.-I., Araki K., Yamato E., Ikegami H., Asano T., Shibasaki Y., Oka Y., Yamamura K.-I.
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms.
Endocrinology 127:126-132(1990)

PubMed=18845907; DOI=10.1507/endocrj.K08E-172
Nakashima K., Kanda Y., Hirokawa Y., Kawasaki F., Matsuki M., Kaku K.
MIN6 is not a pure beta cell line but a mixed cell line with other pancreatic endocrine hormones.
Endocr. J. 56:45-53(2009)

PubMed=22538498; DOI=10.1159/000338793
Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

PubMed=22808281; DOI=10.1371/journal.pone.0040868
Cheng K., Delghingaro-Augusto V., Nolan C.J., Turner N., Hallahan N., Andrikopoulos S., Gunton J.E.
High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation.
PLoS ONE 7:E40868-E40868(2012)

PubMed=25546123; DOI=10.1002/pmic.201400345
Lee J.-S., Wu Y., Schnepp P., Fang J., Zhang X., Karnovsky A., Woods J., Stemmer P.M., Liu M., Zhang K., Chen X.
Proteomics analysis of rough endoplasmic reticulum in pancreatic beta cells.
Proteomics 15:1508-1511(2015)

PubMed=25894527; DOI=10.1371/journal.pone.0121314
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)

Cell line collections AddexBio; C0018008/403
BCRJ; 0293
IBRC; C10524
Cell line databases/resources Lonza; 163
Ontologies BTO; BTO:0002284
EFO; EFO_0002829
MCCL; MCC:0000326
Other Wikidata; Q12513178
Proteomic databases PRIDE; PXD000589
PRIDE; PXD001081
Entry history
Entry creation04-Apr-2012
Last entry update24-May-2019
Version number17