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Cellosaurus MIO-M1 (CVCL_0433)

[Text version]

Cell line name MIO-M1
Synonyms Moorfields/Institute of Ophthalmology-Muller 1
Accession CVCL_0433
Resource Identification Initiative To cite this cell line use: MIO-M1 (RRID:CVCL_0433)
Comments Omics: Deep proteome analysis.
Omics: Metabolome analysis.
Derived from sampling site: Eye; retina; Muller glia.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Spontaneously immortalized cell line
Web pages https://xip.uclb.com/i/materials/MIO_M1_cells.html

Limb G.A., Salt T.E., Munro P.M.G., Moss S.E., Khaw P.T.
In vitro characterization of a spontaneously immortalized human Muller cell line (MIO-M1).
Invest. Ophthalmol. Vis. Sci. 43:864-869(2002)

PubMed=17525239; DOI=10.1634/stemcells.2006-0724
Lawrence J.M., Singhal S., Bhatia B., Keegan D.J., Reh T.A., Luthert P.J., Khaw P.T., Limb G.A.
MIO-M1 cells and similar Muller glial cell lines derived from adult human retina exhibit neural stem cell characteristics.
Stem Cells 25:2033-2043(2007)

Hollborn M., Ulbricht E., Rillich K., Dukic-Stefanovic S., Wurm A., Wagner L., Reichenbach A., Wiedemann P., Limb G.A., Bringmann A., Kohen L.
The human Muller cell line MIO-M1 expresses opsins.
Mol. Vis. 17:2738-2750(2011)

PubMed=30176221; DOI=10.1016/j.exer.2018.08.016
Eastlake K., Heywood W.E., Banerjee P., Bliss E., Mills K., Khaw P.T., Charteris D., Limb G.A.
Comparative proteomic analysis of normal and gliotic PVR retina and contribution of Muller glia to this profile.
Exp. Eye Res. 177:197-207(2018)

PubMed=31254428; DOI=10.1111/ceo.13578
Churm R., Dunseath G.J., Prior S.L., Thomas R.L., Banerjee S., Owens D.R.
Development and characterization of an in vitro system of the human retina using cultured cell lines.
Clin. Exp. Ophthalmol. 47:1055-1062(2019)

PubMed=32152301; DOI=10.1038/s41467-020-15066-6
Singh C., Tran V., McCollum L., Bolok Y., Allan K., Yuan A., Hoppe G., Brunengraber H., Sears J.E.
Hyperoxia induces glutamine-fuelled anaplerosis in retinal Muller cells.
Nat. Commun. 11:1277-1277(2020)

Ontologies BTO; BTO:0003062
MCCL; MCC:0000328
Metabolomic databases MetaboLights; MTBLS1228
Other Wikidata; Q54905749
Proteomic databases PRIDE; PXD008485
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number8