Cellosaurus ML-1 [Human leukemia] (CVCL_0436)

Cell line name ML-1 [Human leukemia]
Synonyms ML1
Accession CVCL_0436
Resource Identification Initiative To cite this cell line use: ML-1 [Human leukemia] (RRID:CVCL_0436)
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1418 ! ML-2
CVCL_H526 ! ML-3
Sex of cell Male
Category Cancer cell line
STR profile Source(s): COG; ECACC

Markers:
AmelogeninX
CSF1PO10,11
D13S3179,12
D16S5399,12
D18S5114,18
D19S43314
D21S1129
D2S133816,17
D3S135815
D5S81812
D7S8209,11
D8S11798,13
FGA23,25
TH017,9.3
TPOX8,10
vWA16
Publications

PubMed=6091813
Palumbo A., Minowada J., Erikson J., Croce C.M., Rovera G.
Lineage infidelity of a human myelogenous leukemia cell line.
Blood 64:1059-1063(1984)

PubMed=3458526
Ohyashiki K., Ohyashiki J.H., Sandberg A.A.
Cytogenetic characterization of putative human myeloblastic leukemia cell lines (ML-1, -2, and -3): origin of the cells.
Cancer Res. 46:3642-3647(1986)

PubMed=8814454; DOI=10.1002/(SICI)1098-2264(199607)16:3<204::AID-GCC8>3.0.CO;2-2
Strout M.P., Mrozek K., Heinonen K., Sait S.N.J., Shows T.B., Aplan P.D.
ML-1 cell line lacks a germline MLL locus.
Genes Chromosomes Cancer 16:204-210(1996)

PubMed=23955599; DOI=10.1038/ng.2731
Kon A., Shih L.-Y., Minamino M., Sanada M., Shiraishi Y., Nagata Y., Yoshida K., Okuno Y., Bando M., Nakato R., Ishikawa S., Sato-Otsubo A., Nagae G., Nishimoto A., Haferlach C., Nowak D., Sato Y., Alpermann T., Nagasaki M., Shimamura T., Tanaka H., Chiba K., Yamamoto R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Nakamaki T., Ishiyama K., Nolte F., Hofmann W.K., Miyawaki S., Chiba S., Mori H., Nakauchi H., Koeffler H.P., Aburatani H., Haferlach T., Shirahige K., Miyano S., Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

Cross-references
Cell line collections ECACC; 88113007
Cell line databases/resources CLDB; cl3489
Ontologies BTO; BTO:0001884
CLO; CLO_0007735
MCCL; MCC:0000331
Polymorphism and mutation databases Cosmic; 787453
Cosmic; 798669
Cosmic; 919125
Cosmic; 924048
Cosmic; 947369
Cosmic; 994171
Cosmic; 998746
Cosmic; 999727
Cosmic; 1037658
Cosmic; 1078735
Cosmic; 1078738
Cosmic; 1127255
Cosmic; 2089662
Cosmic; 2301563