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Cellosaurus ML-1 [Human leukemia] (CVCL_0436)

[Text version]

Cell line name ML-1 [Human leukemia]
Synonyms ML1
Accession CVCL_0436
Resource Identification Initiative To cite this cell line use: ML-1 [Human leukemia] (RRID:CVCL_0436)
Comments Omics: Deep quantitative phosphoproteome analysis.
Derived from sampling site: Peripheral blood.
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1418 ! ML-2
CVCL_H526 ! ML-3
Sex of cell Male
Age at sampling 26Y
Category Cancer cell line
STR profile Source(s): COG; ECACC

Markers:
AmelogeninX
CSF1PO10,11
D2S133816,17
D3S135815
D5S81812
D7S8209,11
D8S11798,13
D13S3179,12
D16S5399,12
D18S5114,18
D19S43314
D21S1129
FGA23,25
TH017,9.3
TPOX8,10
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=6091813; DOI=10.1182/blood.V64.5.1059.1059
Palumbo A., Minowada J., Erikson J., Croce C.M., Rovera G.
Lineage infidelity of a human myelogenous leukemia cell line.
Blood 64:1059-1063(1984)

PubMed=3458526
Ohyashiki K., Ohyashiki J.H., Sandberg A.A.
Cytogenetic characterization of putative human myeloblastic leukemia cell lines (ML-1, -2, and -3): origin of the cells.
Cancer Res. 46:3642-3647(1986)

PubMed=1571549; DOI=10.1182/blood.V79.9.2378.2378
Sugimoto K., Toyoshima H., Sakai R., Miyagawa K., Hagiwara K., Ishikawa F., Takaku F., Yazaki Y., Hirai H.
Frequent mutations in the p53 gene in human myeloid leukemia cell lines.
Blood 79:2378-2383(1992)

PubMed=8814454; DOI=10.1002/(SICI)1098-2264(199607)16:3<204::AID-GCC8>3.0.CO;2-2
Strout M.P., Mrozek K., Heinonen K., Sait S.N.J., Shows T.B., Aplan P.D.
ML-1 cell line lacks a germline MLL locus.
Genes Chromosomes Cancer 16:204-210(1996)

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x
Hosoya N., Hangaishi A., Ogawa S., Miyagawa K., Mitani K., Yazaki Y., Hirai H.
Frameshift mutations of the hMSH6 gene in human leukemia cell lines.
Jpn. J. Cancer Res. 89:33-39(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=21552520; DOI=10.1371/journal.pone.0019169
Gu T.-L., Nardone J., Wang Y., Loriaux M., Villen J., Beausoleil S., Tucker M., Kornhauser J., Ren J., MacNeill J., Gygi S.P., Druker B.J., Heinrich M.C., Rush J., Polakiewicz R.D.
Survey of activated FLT3 signaling in leukemia.
PLoS ONE 6:E19169-E19169(2011)

PubMed=23955599; DOI=10.1038/ng.2731
Kon A., Shih L.-Y., Minamino M., Sanada M., Shiraishi Y., Nagata Y., Yoshida K., Okuno Y., Bando M., Nakato R., Ishikawa S., Sato-Otsubo A., Nagae G., Nishimoto A., Haferlach C., Nowak D., Sato Y., Alpermann T., Nagasaki M., Shimamura T., Tanaka H., Chiba K., Yamamoto R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Nakamaki T., Ishiyama K., Nolte F., Hofmann W.K., Miyawaki S., Chiba S., Mori H., Nakauchi H., Koeffler H.P., Aburatani H., Haferlach T., Shirahige K., Miyano S., Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

Cross-references
Cell line collections ECACC; 88113007
Cell line databases/resources CLDB; cl3489
Cell_Model_Passport; SIDM00440
Ontologies BTO; BTO:0001884
CLO; CLO_0007735
MCCL; MCC:0000331
Other Wikidata; Q54905840
Polymorphism and mutation databases Cosmic; 787453
Cosmic; 798669
Cosmic; 919125
Cosmic; 924048
Cosmic; 947369
Cosmic; 994171
Cosmic; 998746
Cosmic; 999727
Cosmic; 1037658
Cosmic; 1078735
Cosmic; 1078738
Cosmic; 1127255
Cosmic; 2089662
Cosmic; 2301563
Entry history
Entry creation04-Apr-2012
Last entry updated12-Mar-20
Version number16