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Cellosaurus NBT-II (CVCL_0453)

Cell line name NBT-II
Synonyms Nara Bladder Tumor No. 2; Nara Bladder Tumor II; NBTII
Accession CVCL_0453
Resource Identification Initiative To cite this cell line use: NBT-II (RRID:CVCL_0453)
Comments Transformant: ChEBI; CHEBI:91275; N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Rat urinary system neoplasms (NCIt: C60691)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar.
Hierarchy Children:
CVCL_M906 (M-NBT-II)CVCL_4671 (NBT-L1)CVCL_4672 (NBT-L2a)
CVCL_4673 (NBT-L2b)CVCL_4674 (NBT-T1)CVCL_4675 (NBT-T2)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-146.html
Publications

PubMed=4941696; DOI=10.1093/jnci/47.5.979
Toyoshima K., Ito N., Hiasa Y., Kamamoto Y., Makiura S.
Tissue culture of urinary bladder tumor induced in a rat by N-butyl-N-(-4-hydroxybutyl)nitrosamine: establishment of cell line, Nara Bladder Tumor II.
J. Natl. Cancer Inst. 47:979-985(1971)

PubMed=639055
Geisinger K.R., Leighton J., Zealberg J.
Appearance of giant cells as a morphological response of rat bladder carcinoma cell line (Nara Bladder Tumor No. 2) to a continuous thermal gradient in tissue culture.
Cancer Res. 38:1223-1230(1978)

PubMed=6480288
Schroyens W., Bruyneel R., Tchao R., Leighton J., Dragonetti C., Mareel M.M.
Comparison of invasiveness and non-invasiveness of two epithelial cell lines in vitro.
Invasion Metastasis 4:160-170(1984)

PubMed=3567912
Rowley D.R., Tindall D.J.
Responses of NBT-II bladder carcinoma cells to conditioned medium from normal fetal urogenital sinus.
Cancer Res. 47:2955-2960(1987)

PubMed=9369930; DOI=10.1111/j.1349-7006.1997.tb00458.x
Nishi N., Inui M., Kishi Y., Miyanaka H., Wada F.
Isolation and characterization of invasive and noninvasive variants of a rat bladder tumor cell line.
Jpn. J. Cancer Res. 88:831-838(1997)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-1655
ECACC; 93012901
KCLB; 21655
Cell line databases/resources CLO; CLO_0007950
MCCL; MCC:0000351
CLDB; cl3646
Anatomy/cell type resources BTO; BTO:0004316
Encyclopedic resources Wikidata; Q54907562
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number16