Cellosaurus NCI-H292 (CVCL_0455)

Cell line name NCI-H292
Synonyms H292; H-292; NCI-HUT-292; Hut292; NCIH292
Accession CVCL_0455
Resource Identification Initiative To cite this cell line use: NCI-H292 (RRID:CVCL_0455)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: MD Anderson Cell Lines Project.
Microsatellite instability: Instable (MSI-low) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Lung mucoepidermoid carcinoma (NCIt: C45544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B409 (Hut292DM)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D13S31711,12
D16S5399,13
D18S5116
D21S1128
D3S135816
D5S81813
D7S82010
D8S117911,14
FGA22,26
Penta D9
Penta E13,15
TH018
TPOX8,11
vWA16,17
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=8806092; DOI=10.1002/jcb.240630505
Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. 63 Suppl. 24:32-91(1996)

PubMed=15193437; DOI=10.1016/j.cancergencyto.2003.10.007
Tonon G., Gehlhaus K.S., Yonescu R., Kaye F.J., Kirsch I.R.
Multiple reciprocal translocations in salivary gland mucoepidermoid carcinomas.
Cancer Genet. Cytogenet. 152:15-22(2004)

PubMed=17332333; DOI=10.1158/0008-5472.CAN-06-3339
Okabe T., Okamoto I., Tamura K., Terashima M., Yoshida T., Satoh T., Takada M., Fukuoka M., Nakagawa K.
Differential constitutive activation of the epidermal growth factor receptor in non-small cell lung cancer cells bearing EGFR gene mutation and amplification.
Cancer Res. 67:2046-2053(2007)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections ATCC; CRL-1848
BCRC; 60372
BCRJ; 0187
ECACC; 91091815
ICLC; HTL96009
KCB; KCB 200822YJ
KCLB; 21848 - Discontinued
Cell line databases/resources CLDB; cl3653
CLDB; cl3654
CCLE; NCIH292_LUNG
CCRID; 3111C0001CCC000233
CCRID; 3131C0001000700122
Cosmic-CLP; 753604
GDSC; 753604
SKY/M-FISH/CGH; 2844
Ontologies BTO; BTO:0002418
CLO; CLO_0008080
EFO; EFO_0006690
MCCL; MCC:0000353
Biological sample resources BioSample; SAMN03471312
Chemistry resources ChEMBL-Cells; CHEMBL3308637
ChEMBL-Targets; CHEMBL614733
Gene expression databases GEO; GSM206489
GEO; GSM274745
GEO; GSM274746
GEO; GSM784237
GEO; GSM794281
GEO; GSM888505
GEO; GSM1670237
GEO; GSM2231213
Polymorphism and mutation databases Cosmic; 753604
Cosmic; 844598
Cosmic; 877404
Cosmic; 1017828
Cosmic; 1047099
Cosmic; 1152499
Cosmic; 1188584
Cosmic; 1288262
Cosmic; 1466803
Cosmic; 1519249
Cosmic; 1520933
Cosmic; 1520947
Cosmic; 1870272
Cosmic; 1995573
Cosmic; 2630420