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Cellosaurus NCTC clone 929 (CVCL_0462)

[Text version]

Cell line name NCTC clone 929
Synonyms NCTC 929; NCTC-929; NCTC929; L cell; L cells; L-cell; L-cells; L cell line; L; Strain L-929; L-929; L 929; L929; L929(NCTC); Clone 929; Earles's cells; Earle's L cells
Accession CVCL_0462
Resource Identification Initiative To cite this cell line use: NCTC clone 929 (RRID:CVCL_0462)
Comments Group: Space-flown cell line (cellonaut).
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Doubling time: 28 hours (from cell counting), 32 hours (from absorbance) (DOI=10.5897/IJBMBR2013.0154); ~25 hours (CLS); ~21-24 hours (DSMZ).
Anecdotal: First established continuous cell line.
Miscellaneous: PubMed=23430347 has a different value for STR 6-4 (16) than that of NIST (17,18) due to a change in the marker motif (personal communication of Almeida J.L.).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/An.
Hierarchy Children:
CVCL_DD99 (1R)CVCL_3984 (A-9)CVCL_4114 (B82)
CVCL_8887 (L Cells (TK+, HBS Ag+))CVCL_IW04 (L-929 D)CVCL_IW05 (L-929 E)
CVCL_IW06 (L-929 F)CVCL_IW07 (L-929 HH)CVCL_4535 (L-M)
CVCL_U990 (L.P3)CVCL_0D72 (L4.5)CVCL_AR58 (L929/A)
CVCL_4237 (L929/R)CVCL_4238 (L929S)CVCL_4Z39 (LA-9)
CVCL_B950 (LAG)CVCL_WY44 (LMCAT)CVCL_3742 (McCoy)
CVCL_4255 (NCTC 2071)
Sex of cell Male
Age at sampling 100D
Category Spontaneously immortalized cell line
STR profile Source(s): PubMed=23430347; PubMed=31220119

Markers:
Mouse STR 1-110
Mouse STR 1-217
Mouse STR 2-19
Mouse STR 3-213,14
Mouse STR 4-220.3
Mouse STR 5-514
Mouse STR 6-417,18
Mouse STR 6-712
Mouse STR 7-125,26,27
Mouse STR 8-116
Mouse STR 9-215
Mouse STR 11-215,16
Mouse STR 12-116
Mouse STR 13-117
Mouse STR 15-324.3,25.3,26.3
Mouse STR 17-215
Mouse STR 18-316
Mouse STR 19-212
Mouse STR X-126,27

Run an STR similarity search on this cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=L929
http://en.vircell.com/products/l-929-cell-line/
http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-125.html
https://www.researchgate.net/post/Is_L929_normal_or_cancer_cell_line
http://www.cellresource.cn/fdetail.aspx?id=391
http://www.cellresource.cn/fdetail.aspx?id=498
http://www.cellresource.cn/fdetail.aspx?id=802
http://www.cellresource.cn/fdetail.aspx?id=1296
http://www.cellresource.cn/fdetail.aspx?id=1671
http://www.cellresource.cn/fdetail.aspx?id=2022
Publications

PubMed=18105872; DOI=10.1093/jnci/9.3.229
Sanford K.K., Earle W.R., Likely G.D.
The growth in vitro of single isolated tissue cells.
J. Natl. Cancer Inst. 9:229-246(1948)

PubMed=13293658
Sanford K.K., Hobbs G.L., Earle W.R.
The tumor-producing capacity of strain L mouse cells after 10 years in vitro.
Cancer Res. 16:162-166(1956)

PubMed=14185313; DOI=10.1126/science.146.3641.241
Cell Culture Collection Committee
Animal cell strains. The Cell Culture Collection Committee has assembled and certified 23 strains of animal cells.
Science 146:241-243(1964)

PubMed=4328993; DOI=10.1016/0014-4827(71)90412-5
Takaoka T., Katsuta H.
Long-term cultivation of mammalian cell strains in protein- and lipid-free chemically defined synthetic media.
Exp. Cell Res. 67:295-304(1971)

PubMed=4560675
Tsuboi K., Takaoka T., Katsuta H.
Comparative analyses of strain L-929 and its substrain L-P3 grown in a protein-and lipid-free synthetic medium.
Jpn. J. Exp. Med. 42:361-376(1972)

PubMed=4471172; DOI=10.1007/BF02615345
Ham R.G.
Nutritional requirements of primary cultures. A neglected problem of modern biology.
In Vitro 10:119-129(1974)

PubMed=6298990; DOI=10.1016/0378-1135(82)90056-6
McPhee D.A., Parsonson I.M., Della-Porta A.J.
Comparative studies on the growth of Australian bluetongue virus serotypes in continuous cell lines and embryonated chicken eggs.
Vet. Microbiol. 7:401-410(1982)

DOI=10.4051/ibc.2010.2.4.0014
Yoshino K., Saijo K., Noro C., Nakamura Y.
Development of a simple method to determine the mouse strain from which cultured cell lines originated.
Interdisciplinary Bio Central 2:1-9(2010)

DOI=10.5897/IJBMBR2013.0154
Iloki Assanga S.B., Gil-Salido A.A., Lewis Lujan L.M., Rosas-Durazo A., Acosta-Silva A.L., Rivera-Castaneda E.G., Rubio-Pino J.L.
Cell growth curves for different cell lines and their relationship with biological activities.
Int. J. Biotechnol. Mol. Biol. Res. 4:60-70(2013)

PubMed=23430347; DOI=10.1007/s10616-013-9545-7
Almeida J.L., Hill C.R., Cole K.D.
Mouse cell line authentication.
Cytotechnology 66:133-147(2014)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line collections AddexBio; P0011012/5025
ATCC; CCL-1
ATCC; CRL-6364 - Discontinued
BCRC; 60091
BCRJ; 0188
CCLV; CCLV-RIE 0014
CCLV; CCLV-RIE 0287
CCTCC; GDC0034
CLS; 400260/p757_L-929
DSMZ; ACC-2
ECACC; 85011425
ECACC; 85103115
ECACC; 88102702
IBRC; C10102
ICLC; ATL95001
IZSLER; BS CL 56
JCRB; IFO50409
JCRB; JCRB9003
KCB; KCB 92012YJ
KCLB; 10001
NCBI_Iran; C161
RCB; RCB0081 - Discontinued
RCB; RCB1422
RCB; RCB1451
RCB; RCB2619
TKG; TKG 0217
Cell line databases/resources CLDB; cl3154
CLDB; cl3156
CLDB; cl3157
CLDB; cl3158
CLDB; cl3159
CLDB; cl3160
CLDB; cl3673
CLDB; cl3674
CLDB; cl3675
CLDB; cl3676
CCRID; 3111C0001CCC000403
CCRID; 3111C0002000000019
CCRID; 3131C0001000300010
CCRID; 3131C0001000300028
CCRID; 3142C0001000000034
CCRID; 3153C0001000000022
FCS-free; 8-5-9-1-3-3
FCS-free; 8-5-530-1-3-3
Lonza; 32
Lonza; 937
TOKU-E; 3695
Ontologies BTO; BTO:0000331
CLO; CLO_0007144
CLO; CLO_0007219
CLO; CLO_0007220
CLO; CLO_0007221
CLO; CLO_0008140
CLO; CLO_0050233
CLO; CLO_0050234
CLO; CLO_0050235
MCCL; MCC:0000359
MeSH; D007739
Biological sample resources BioSample; SAMN11397622
Chemistry resources ChEMBL-Cells; CHEMBL3307759
ChEMBL-Cells; CHEMBL3307946
ChEMBL-Targets; CHEMBL612266
ChEMBL-Targets; CHEMBL612267
Other Wikidata; Q28335098
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number28