ID   NCTC clone 929
AC   CVCL_0462
SY   NCTC 929; NCTC-929; NCTC929; NCTC-929L; L cell; L cells; L-cell; L-cells; L cell line; L; Strain L-929; L-929; L 929; L929; L929(NCTC); Clone 929; Earles's cells; Earle's L cells
DR   BTO; BTO:0000331
DR   CLO; CLO_0007144
DR   CLO; CLO_0007219
DR   CLO; CLO_0007220
DR   CLO; CLO_0007221
DR   CLO; CLO_0008140
DR   CLO; CLO_0050233
DR   CLO; CLO_0050234
DR   CLO; CLO_0050235
DR   MCCL; MCC:0000359
DR   CLDB; cl3154
DR   CLDB; cl3156
DR   CLDB; cl3157
DR   CLDB; cl3158
DR   CLDB; cl3159
DR   CLDB; cl3160
DR   CLDB; cl3673
DR   CLDB; cl3674
DR   CLDB; cl3675
DR   CLDB; cl3676
DR   AddexBio; P0011012/5025
DR   ATCC; CCL-1
DR   ATCC; CRL-6364
DR   BCRC; 60091
DR   BCRJ; 0188
DR   BioGRID_ORCS_Cell_line; 1749
DR   BioSample; SAMN11397622
DR   CCLV; CCLV-RIE 0014
DR   CCLV; CCLV-RIE 0287
DR   CCRID; 1101MOU-PUMC000403
DR   CCRID; 1102MOU-NIFDC00019
DR   CCRID; 3101MOUGNM28
DR   CCRID; 3101MOUSCSP5039
DR   CCRID; 4201MOU-CCTCC00034
DR   CCRID; 5301MOU-KCB92012YJ
DR   CCTCC; GDC0034
DR   ChEMBL-Cells; CHEMBL3307946
DR   ChEMBL-Targets; CHEMBL612266
DR   ChEMBL-Targets; CHEMBL612267
DR   CLS; 400260
DR   DSMZ; ACC-2
DR   DSMZCellDive; ACC-2
DR   ECACC; 85011425
DR   ECACC; 85103115
DR   ECACC; 88102702
DR   FCS-free; 8-5-9-1-3-3
DR   FCS-free; 8-5-530-1-3-3
DR   IBRC; C10102
DR   ICLC; ATL95001
DR   IZSLER; BS CL 56
DR   JCRB; IFO50409
DR   JCRB; JCRB9003
DR   KCB; KCB 92012YJ
DR   KCLB; 10001
DR   Lonza; 32
DR   Lonza; 937
DR   MeSH; D007739
DR   NCBI_Iran; C161
DR   PubChem_Cell_line; CVCL_0462
DR   RCB; RCB0081
DR   RCB; RCB1422
DR   RCB; RCB1451
DR   RCB; RCB2619
DR   TKG; TKG 0217
DR   TOKU-E; 3695
DR   Ubigene; YC-C091
DR   Wikidata; Q28335098
RX   DOI=10.1007/BF02618370;
RX   DOI=10.4051/ibc.2010.2.4.0014;
RX   DOI=10.5897/IJBMBR2013.0154;
RX   PubMed=4328993;
RX   PubMed=4471172;
RX   PubMed=4560675;
RX   PubMed=6298990;
RX   PubMed=13293658;
RX   PubMed=13431913;
RX   PubMed=13587550;
RX   PubMed=14185313;
RX   PubMed=18105872;
RX   PubMed=23430347;
RX   PubMed=31220119;
RX   PubMed=32218446;
RX   PubMed=33389257;
RX   PubMed=34737324;
WW   http://www.cells-talk.com/index.php/page/copelibrary?key=L929
WW   https://en.vircell.com/products/l-929-cell-line/
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-125.html
WW   https://www.researchgate.net/post/Is_L929_normal_or_cancer_cell_line
CC   Group: Space-flown cell line (cellonaut).
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
CC   Doubling time: 28 hours (Note=From cell counting), 32 hours (Note=From absorbance) (DOI=10.5897/IJBMBR2013.0154); ~25 hours (CLS=400260); ~21-24 hours (DSMZ=ACC-2).
CC   Omics: Deep quantitative proteome analysis.
CC   Anecdotal: First established continuous cell line.
CC   Miscellaneous: PubMed=23430347 has a different value for STR 6-4 (16) than that of NIST (17,18) due to a change in the marker motif (personal communication of Almeida J.L.).
CC   Discontinued: ATCC; CRL-6364; true.
CC   Discontinued: RCB; RCB0081; true.
CC   Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: C3H/An.
ST   Source(s): DSMZ; PubMed=23430347; PubMed=31220119; Ubigene
ST   Mouse STR 1-1: 10
ST   Mouse STR 1-2: 17
ST   Mouse STR 11-2: 15,16
ST   Mouse STR 12-1: 16
ST   Mouse STR 13-1: 17
ST   Mouse STR 15-3: 24.3,25.3,26.3
ST   Mouse STR 17-2: 15
ST   Mouse STR 18-3: 16
ST   Mouse STR 19-2: 12
ST   Mouse STR 2-1: 9
ST   Mouse STR 3-2: 13,14
ST   Mouse STR 4-2: 20.3
ST   Mouse STR 5-5: 14
ST   Mouse STR 6-4: 16,17 (DSMZ)
ST   Mouse STR 6-4: 17,18 (PubMed=23430347; PubMed=31220119; Ubigene)
ST   Mouse STR 6-7: 12
ST   Mouse STR 7-1: 25,26,27
ST   Mouse STR 8-1: 16
ST   Mouse STR 9-2: 15
ST   Mouse STR X-1: 26,27
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   100D
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 39
//
RX   DOI=10.1007/BF02618370;
RA   Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.;
RT   "The animal cell culture collection.";
RL   In Vitro 5:1-16(1970).
//
RX   DOI=10.4051/ibc.2010.2.4.0014;
RA   Yoshino K., Saijo K., Noro C., Nakamura Y.;
RT   "Development of a simple method to determine the mouse strain from which
RT   cultured cell lines originated.";
RL   Interdisciplinary Bio Central 2:1-9(2010).
//
RX   DOI=10.5897/IJBMBR2013.0154;
RA   Iloki Assanga S.B., Gil-Salido A.A., Lewis Lujan L.M., Rosas-Durazo A.,
RA   Acosta-Silva A.L., Rivera-Castaneda E.G., Rubio-Pino J.L.;
RT   "Cell growth curves for different cell lines and their relationship
RT   with biological activities.";
RL   Int. J. Biotechnol. Mol. Biol. Res. 4:60-70(2013).
//
RX   PubMed=4328993; DOI=10.1016/0014-4827(71)90412-5;
RA   Takaoka T., Katsuta H.;
RT   "Long-term cultivation of mammalian cell strains in protein- and
RT   lipid-free chemically defined synthetic media.";
RL   Exp. Cell Res. 67:295-304(1971).
//
RX   PubMed=4471172; DOI=10.1007/BF02615345;
RA   Ham R.G.;
RT   "Nutritional requirements of primary cultures. A neglected problem of
RT   modern biology.";
RL   In Vitro 10:119-129(1974).
//
RX   PubMed=4560675;
RA   Tsuboi K., Takaoka T., Katsuta H.;
RT   "Comparative analyses of strain L-929 and its substrain L-P3 grown in
RT   a protein-and lipid-free synthetic medium.";
RL   Jpn. J. Exp. Med. 42:361-376(1972).
//
RX   PubMed=6298990; DOI=10.1016/0378-1135(82)90056-6;
RA   McPhee D.A., Parsonson I.M., Della-Porta A.J.;
RT   "Comparative studies on the growth of Australian bluetongue virus
RT   serotypes in continuous cell lines and embryonated chicken eggs.";
RL   Vet. Microbiol. 7:401-410(1982).
//
RX   PubMed=13293658;
RA   Sanford K.K., Hobbs G.L., Earle W.R.;
RT   "The tumor-producing capacity of strain L mouse cells after 10 years
RT   in vitro.";
RL   Cancer Res. 16:162-166(1956).
//
RX   PubMed=13431913; DOI=10.3181/00379727-94-23044;
RA   Foley G.E., Handler A.H.;
RT   "Differentiation of normal and neoplastic cells maintained in tissue
RT   culture by implantation into normal hamsters.";
RL   Proc. Soc. Exp. Biol. Med. 94:661-664(1957).
//
RX   PubMed=13587550; DOI=10.1083/jcb.4.5.567;
RA   Westfall B.B., Peppers E.V., Evans V.J., Sanford K.K., Hawkins N.M.,
RA   Fioramonti M.C., Kerr H.A., Hobbs G.L., Earle W.R.;
RT   "The arginase and rhodanese activities of certain cell strains after
RT   long cultivation in vitro.";
RL   J. Biophys. Biochem. Cytol. 4:567-570(1958).
//
RX   PubMed=14185313; DOI=10.1126/science.146.3641.241;
RG   Cell Culture Collection Committee;
RT   "Animal cell strains. The Cell Culture Collection Committee has
RT   assembled and certified 23 strains of animal cells.";
RL   Science 146:241-243(1964).
//
RX   PubMed=18105872; DOI=10.1093/jnci/9.3.229;
RA   Sanford K.K., Earle W.R., Hobbs G.L.;
RT   "The growth in vitro of single isolated tissue cells.";
RL   J. Natl. Cancer Inst. 9:229-246(1948).
//
RX   PubMed=23430347; DOI=10.1007/s10616-013-9545-7;
RA   Almeida J.L., Hill C.R., Cole K.D.;
RT   "Mouse cell line authentication.";
RL   Cytotechnology 66:133-147(2014).
//
RX   PubMed=31220119; DOI=10.1371/journal.pone.0218412;
RA   Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S.,
RA   Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H.,
RA   Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B.,
RA   Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.;
RT   "Interlaboratory study to validate a STR profiling method for
RT   intraspecies identification of mouse cell lines.";
RL   PLoS ONE 14:E0218412-E0218412(2019).
//
RX   PubMed=32218446; DOI=10.1038/s41597-020-0449-z;
RA   Zhong C.-Q., Wu J.-F., Qiu X.-F., Chen X., Xie C.-C., Han J.-H.;
RT   "Generation of a murine SWATH-MS spectral library to quantify more
RT   than 11,000 proteins.";
RL   Sci. Data 7:104-104(2020).
//
RX   PubMed=33389257; DOI=10.1007/s10096-020-04106-0;
RA   Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.;
RT   "Culture of SARS-CoV-2 in a panel of laboratory cell lines,
RT   permissivity, and differences in growth profile.";
RL   Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021).
//
RX   PubMed=34737324; DOI=10.1038/s41598-021-00779-5;
RA   Lung O., Candlish R.C., Nebroski M., Kruckiewicz P., Buchanan C.,
RA   Moniwa M.;
RT   "High-throughput sequencing for species authentication and
RT   contamination detection of 63 cell lines.";
RL   Sci. Rep. 11:21657-21657(2021).
//