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Cellosaurus Neuro-2a (CVCL_0470)

[Text version]

Cell line name Neuro-2a
Synonyms NEURO-2A; Neuro 2a; Neuro2a; Neuro2A; N-2a; N2a; N2A; Nb2a; NB2a
Accession CVCL_0470
Resource Identification Initiative To cite this cell line use: Neuro-2a (RRID:CVCL_0470)
Comments Characteristics: Capable of differentiating into various types of neurons.
Doubling time: ~70 hours (DSMZ).
Omics: Deep proteome analysis.
Omics: SNP array analysis.
Disease Mouse neuroblastoma (NCIt: C21993)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: A/J.
Hierarchy Parent: CVCL_4343 (C-1300)
CVCL_6246 (AGN2a)CVCL_4510 (C1300 CLONE NA)CVCL_ZM10 (N2A FLAG-Cdh1)
CVCL_WI11 (N2a-R33)CVCL_WI08 (N2a/Gary)CVCL_D649 (N2aEGFP)
CVCL_D650 (N2aSW)CVCL_RW97 (Na 42/13)CVCL_B436 (NB2a/d1)
CVCL_DF49 (Neuro-2a NucLight Green)CVCL_DF50 (Neuro-2a NucLight Red)CVCL_K046 (Neuro-2a-Luc)
CVCL_A9J5 (Neuro-2a/CMV-Luc)CVCL_F275 (Neuro-2aTG)CVCL_6268 (ScN2a)
Sex of cell Male
Category Cancer cell line
Web pages https://en.wikipedia.org/wiki/N2a_cell

PubMed=11470893; DOI=10.1073/pnas.151242598
Enari M., Flechsig E., Weissmann C.
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody.
Proc. Natl. Acad. Sci. U.S.A. 98:9295-9299(2001)

PubMed=14504404; DOI=10.1073/pnas.1834432100
Klohn P.-C., Stoltze L., Flechsig E., Enari M., Weissmann C.
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions.
Proc. Natl. Acad. Sci. U.S.A. 100:11666-11671(2003)

PubMed=19903493; DOI=10.1016/j.jneumeth.2009.11.004
Tremblay R.G., Sikorska M., Sandhu J.K., Lanthier P., Ribecco-Lutkiewicz M., Bani-Yaghoub M.
Differentiation of mouse Neuro 2A cells into dopamine neurons.
J. Neurosci. Methods 186:60-67(2010)

PubMed=25193168; DOI=10.1074/mcp.M113.037291
Hornburg D., Drepper C., Butter F., Meissner F., Sendtner M., Mann M.
Deep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics.
Mol. Cell. Proteomics 13:3410-3420(2014)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

PubMed=25565633; DOI=10.1371/journal.pone.0117154
Oelschlegel A.M., Geissen M., Lenk M., Riebe R., Angermann M., Schaetzl H., Groschup M.H.
A bovine cell line that can be infected by natural sheep scrapie prions.
PLoS ONE 10:E0117154-E0117154(2015)

Cell line collections ATCC; CCL-131
BCRC; 60026
BCRJ; 0189
CLS; 400394/p451_Neuro-2A
ECACC; 89121404
ICLC; ATL99007
JCRB; IFO50081
KCB; KCB 2014025YJ
RCB; RCB2639
TKG; TKG 0509
Cell line databases/resources CLDB; cl3682
CLDB; cl3683
CLDB; cl3684
CLDB; cl3685
CLDB; cl4956
CLDB; cl5236
CCRID; 3111C0001CCC000291
CCRID; 3131C0001000800029
CCRID; 3142C0001000001719
Lonza; 451
TOKU-E; 2746
TOKU-E; 3552
TOKU-E; 3563
Ontologies BTO; BTO:0001976
CLO; CLO_0008154
CLO; CLO_0050180
MCCL; MCC:0000368
Chemistry resources ChEMBL-Cells; CHEMBL3307521
ChEMBL-Targets; CHEMBL614062
Other Wikidata; Q18391478
Proteomic databases PRIDE; PXD000065
PRIDE; PXD002290
PRIDE; PXD018875
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number25