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Cellosaurus OK (CVCL_0472)

Cell line name OK
Synonyms Opossum Kidney; OK-WT
Accession CVCL_0472
Resource Identification Initiative To cite this cell line use: OK (RRID:CVCL_0472)
Comments Group: Marsupial cell line.
Characteristics: Used to study X chromosome inactivation as well as to investigate proximal tubule ion transport and membrane trafficking.
Doubling time: 18 hours (PubMed=566717).
Omics: Deep RNAseq analysis.
Omics: Transcriptome analysis.
Species of origin Didelphis virginiana (North American opossum) (Didelphis marsupialis virginiana) (NCBI Taxonomy: 9267)
Hierarchy Children:
CVCL_W411 (OK7A)CVCL_D041 (OKB)CVCL_D042 (OKH)
CVCL_D040 (OKP)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages https://en.wikipedia.org/wiki/OK_cells
http://fluoview.magnet.fsu.edu/gallery/cells/ok/okcells.html
http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/o/cell-lines-detail-497.html
Publications

PubMed=566717; DOI=10.1007/BF02616032
Koyama H., Goodpasture C., Miller M.M., Teplitz R.L., Riggs A.D.
Establishment and characterization of a cell line from the American opossum (Didelphys virginiana).
In Vitro 14:239-246(1978)

PubMed=6394469; DOI=10.1007/BF02619628
Keith D.H., Teplitz R.L., Riggs A.D.
Metaphase synchronization and chromosome preparation from the OK opossum cell line having a potentially isolatable X chromosome.
In Vitro 20:833-836(1984)

PubMed=1802405; DOI=10.1016/0309-1651(91)90094-Y
Courjault F., Gerin B., Leroy D., Chevalier J., Toutain H.
Morphological and biochemical characterization of the opossum kidney cell line and primary cultures of rabbit proximal tubule cells in serum-free defined medium.
Cell Biol. Int. Rep. 15:1225-1234(1991)

PubMed=28615248; DOI=10.1152/ajprenal.00228.2017
Eshbach M.L., Sethi R., Avula R., Lamb J., Hollingshead D.J., Finegold D.N., Locker J., Chandran U.R., Weisz O.A.
The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line.
Am. J. Physiol. Renal Physiol. 313:F585-F595(2017)

Cross-references
Cell line collections ATCC; CRL-1840
CLS; 606465/p702_OK
ECACC; 91021202
KCB; KCB 200824YJ
Cell line databases/resources CLDB; cl3766
CCRID; 3131C0001000400020
TOKU-E; 2794
Ontologies BTO; BTO:0003069
CLO; CLO_0008246
MCCL; MCC:0000370
Other Wikidata; Q25326634