Cellosaurus OV-2008 (CVCL_0473)

Cell line name OV-2008
Synonyms OV2008; Ov2008; OV 2008; 2008; A2008
Accession CVCL_0473
Secondary accession CVCL_4066
Resource Identification Initiative To cite this cell line use: OV-2008 (RRID:CVCL_0473)
Comments Problematic cell line: Contaminated. Shown to be a ME-180 derivative (PubMed=22570425).
Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
Omics: Transcriptome analysis.
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Derived from metastatic site: Omentum.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1401 (ME-180)
Children: CVCL_0114 (2008/C13*5.25); CVCL_W373 (PX2); CVCL_W374 (PX24)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=22710073

Markers:
AmelogeninX
CSF1PO11
D13S31711,12
D16S53912,13
D18S5112
D19S43313,15.2
D21S1130,31
D2S133818
D3S135816
D5S81812
D7S8209,10
D8S117914
FGA23
TH018,9.3
TPOX8,10
vWA15,17
Web pages http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/2/cell-lines-detail-62.html
http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=4118903; DOI=10.1016/0002-9378(72)90109-3
DiSaia P.J., Sinkovics J.G., Rutledge F.N., Smith J.P.
Cell-mediated immunity to human malignant cells. A brief review and further studies with two gynecologic tumors.
Am. J. Obstet. Gynecol. 114:979-989(1972)

PubMed=9234707; DOI=10.1128/MCB.17.8.4501
Bullions L.C., Notterman D.A., Chung L.S., Levine A.J.
Expression of wild-type alpha-catenin protein in cells with a mutant alpha-catenin gene restores both growth regulation and tumor suppressor activities.
Mol. Cell. Biol. 17:4501-4508(1997)

PubMed=11314036; DOI=10.1038/sj.onc.1204211
Forgacs E., Wren J.D., Kamibayashi C., Kondo M., Xu X.L., Markowitz S.D., Tomlinson G.E., Muller C.Y., Gazdar A.F., Garner H.R., Minna J.D.
Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.
Oncogene 20:1005-1009(2001)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=24023729; DOI=10.1371/journal.pone.0072162
Anglesio M.S., Wiegand K.C., Melnyk N., Chow C., Salamanca C.M., Prentice L.M., Senz J., Yang W., Spillman M.A., Cochrane D.R., Shumansky K., Shah S.P., Kalloger S.E., Huntsman D.G.
Type-specific cell line models for type-specific ovarian cancer research.
PLoS ONE 8:E72162-E72162(2013)

Cross-references
Ontologies BTO; BTO:0003792
MCCL; MCC:0000371
Biological sample resources BioSample; SAMN03151841
BioSample; SAMN03151843
Chemistry resources ChEMBL-Cells; CHEMBL3308015
ChEMBL-Targets; CHEMBL612818
Gene expression databases GEO; GSM184384
GEO; GSM184385
GEO; GSM659387
GEO; GSM851907
GEO; GSM851925
Polymorphism and mutation databases Cosmic; 849613
Cosmic; 948293
Cosmic; 988874
Cosmic; 1102825
Cosmic; 1524359
Cosmic; 1707563
Cosmic; 2582806