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Cellosaurus SG231 (CVCL_0519)

[Text version]
Cell line name SG231
Synonyms PCI:SG231; PCI-SG231; PCI:SG-231
Accession CVCL_0519
Resource Identification Initiative To cite this cell line use: SG231 (RRID:CVCL_0519)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Deep exome analysis.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Thr125Pro (c.373A>C); ClinVar=VCV000376666; Zygosity=Unspecified (DepMap).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): ATCC; DepMap

Markers:
AmelogeninX
CSF1PO10 (ATCC)
10,11 (DepMap)
D3S135817
D5S81812
D7S82011
D8S117912,13
D13S3179,10
D16S5399,14 (DepMap)
14 (ATCC)
D18S5118
D21S1129
FGA21,21.2
Penta D12,15
Penta E10,13
TH018,9
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=2176543; DOI=10.1002/gcc.2870020408
Storto P.D., Saidman S.L., Demetris A.J., Letessier E., Whiteside T.L., Gollin S.M.
Chromosomal breakpoints in cholangiocarcinoma cell lines.
Genes Chromosomes Cancer 2:300-310(1990)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442
Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C., Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K., Greninger P., McDermott U., Garnett M.J., Jenkins R.L., Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y., Goyal L., Ferrone C.R., Zhu A.X., Joung J.K., Shokat K.M., Benes C.H., El-Bardeesy N.
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-2126 - Discontinued
Cell line databases/resources MCCL; MCC:0000417
cancercelllines; CVCL_0519
Cell_Model_Passport; SIDM01852
DepMap; ACH-001857
Anatomy/cell type resources BTO; BTO:0002935
Biological sample resources BioSample; SAMN03472551
Encyclopedic resources Wikidata; Q54953156
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number22