Cell line name | SK-N-BE(2)-C | ||||||||||||||||||
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Synonyms | SK-N-BE(2)C; SK-N-BE-2c; SK-N-BE(2C); SK-N-BE(2c); SK-N-BE2C; SK_N_BE2C; SKNBE2C; SKNBE(2c); BE(2)-C; BE(2)C; Be(2)C; BE2-C; BE2_C; Be2-C; BE2C; Be2C | ||||||||||||||||||
Accession | CVCL_0529 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: SK-N-BE(2)-C (RRID:CVCL_0529) | ||||||||||||||||||
Comments | Part of: ENCODE project common cell types; tier 3. From: Memorial Sloan Kettering Cancer Center; New York; USA. Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK1980-532. Characteristics: Intermediate type (I-type) (PubMed=15720811). Omics: Array-based CGH. Omics: ATAC-seq. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: H3K27ac ChIP-seq epigenome analysis. Omics: H3K27me3 ChIP-seq epigenome analysis. Omics: H3K4me1 ChIP-seq epigenome analysis. Omics: H3K4me3 ChIP-seq epigenome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||
Sequence variations | Homozygous for TP53 p.Cys135Phe (c.404G>T) (ClinVar=VCV000376559) (from parent cell line). | ||||||||||||||||||
Disease | Neuroblastoma (NCIt: C3270) Neuroblastoma (ORDO: Orphanet_635) Derived from metastatic site: Bone marrow. | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Parent: CVCL_0528 (SK-N-BE(2)) Children:
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Sex of cell | Male | ||||||||||||||||||
Age at sampling | 1Y10M | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): ATCC; ECACC Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | http://genome.ucsc.edu/ENCODE/protocols/cell/human/BE2-C_Myers_protocol.pdf http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-162.html https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-n-be-2-c-human-neuroblastoma-cell-line | ||||||||||||||||||
Publications | PubMed=6582512; DOI=10.1073/pnas.81.2.568 PubMed=2535691 PubMed=1985865; DOI=10.1002/ijc.2910470119 PubMed=10630978; DOI=10.1667/0033-7587(2000)153[0062:FORIMI]2.0.CO;2 PubMed=15720811; DOI=10.1593/neo.04310 PubMed=15892104; DOI=10.1002/gcc.20198 PubMed=18724359; DOI=10.1038/nature07261 PubMed=19147553; DOI=10.1158/0008-5472.CAN-08-1856 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=23202128; DOI=10.1038/ng.2493 PubMed=23325432; DOI=10.1101/gr.147942.112 PubMed=24466371; DOI=10.1593/tlo.13544 PubMed=26342562; DOI=10.1016/j.scr.2015.08.008 PubMed=28350380; DOI=10.1038/sdata.2017.33 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | ATCC; CRL-2268
ECACC; 95011817 ICLC; HTL96018 NCBI_Iran; C577 | ||||||||||||||||||
Cell line databases/resources | CLDB; cl413
CLDB; cl4334 Cell_Model_Passport; SIDM01232 IGRhCellID; BE2C LINCS_LDP; LCL-1963 | ||||||||||||||||||
Ontologies | BTO; BTO:0004782
CLO; CLO_0001915 CLO; CLO_0009053 EFO; EFO_0005725 MCCL; MCC:0000428 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03471855
ENCODE; ENCBS271SFD ENCODE; ENCBS403ENC ENCODE; ENCBS427ENC ENCODE; ENCBS982TUR | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
GEO; GSM651567 GEO; GSM651568 GEO; GSM945241 GEO; GSM945283 GEO; GSM923434 GEO; GSM2371256 GEO; GSM2394383 GEO; GSM4104593 GEO; GSM4104594 GEO; GSM4105343 GEO; GSM4105344 GEO; GSM4105345 GEO; GSM4105346 GEO; GSM4105347 | ||||||||||||||||||
Other | Wikidata; Q54954443 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 688061
Cosmic; 922659 Cosmic; 1162003 Cosmic; 1167421 Cosmic; 1526648 Progenetix; CVCL_0529 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD003596 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||
Version number | 29 |