ID   SK-N-SH
AC   CVCL_0531
SY   SK N SH; SKN-SH; SK-NSH; SKNSH; NSH
DR   BTO; BTO:0001620
DR   CLO; CLO_0009059
DR   CLO; CLO_0050268
DR   EFO; EFO_0003072
DR   MCCL; MCC:0000430
DR   CLDB; cl4345
DR   CLDB; cl4347
DR   CLDB; cl4348
DR   CLDB; cl4349
DR   CLDB; cl4351
DR   CLDB; cl4352
DR   AddexBio; C0005006/4924
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; HTB-11
DR   BioGRID_ORCS_Cell_line; 1014
DR   BioSample; SAMN01821600
DR   BioSample; SAMN03472879
DR   BioSample; SAMN10987849
DR   cancercelllines; CVCL_0531
DR   CCRID; 1101HUM-PUMC000086
DR   CCRID; 3101HUMSCSP5029
DR   CCRID; 3101HUMTCHu51
DR   CCRID; 4201HUM-CCTCC00047
DR   CCTCC; GDC0047
DR   Cell_Model_Passport; SIDM01098
DR   CGH-DB; 62-1
DR   CGH-DB; 9093-4
DR   ChEMBL-Cells; CHEMBL3307745
DR   ChEMBL-Targets; CHEMBL614924
DR   CLS; 305028
DR   Cosmic; 697284
DR   Cosmic; 717431
DR   Cosmic; 801743
DR   Cosmic; 848936
DR   Cosmic; 922656
DR   Cosmic; 923830
DR   Cosmic; 930078
DR   Cosmic; 947706
DR   Cosmic; 1019929
DR   Cosmic; 1037355
DR   Cosmic; 1078393
DR   Cosmic; 1082519
DR   Cosmic; 1099151
DR   Cosmic; 1109108
DR   Cosmic; 1109371
DR   Cosmic; 1153800
DR   Cosmic; 1153806
DR   Cosmic; 1162006
DR   Cosmic; 1167420
DR   Cosmic; 1167993
DR   Cosmic; 1518079
DR   Cosmic; 1526640
DR   Cosmic; 2058116
DR   Cosmic; 2131595
DR   Cosmic; 2239469
DR   Cosmic; 2393645
DR   Cosmic; 2485952
DR   Cosmic-CLP; 717431
DR   DepMap; ACH-000149
DR   ECACC; 86012802
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   ENCODE; ENCBS007RAH
DR   ENCODE; ENCBS018DDZ
DR   ENCODE; ENCBS061YYT
DR   ENCODE; ENCBS324TZB
DR   ENCODE; ENCBS360ENC
DR   ENCODE; ENCBS361ENC
DR   ENCODE; ENCBS362ENC
DR   ENCODE; ENCBS363ENC
DR   ENCODE; ENCBS364ENC
DR   ENCODE; ENCBS365ENC
DR   ENCODE; ENCBS376ENC
DR   ENCODE; ENCBS387WHS
DR   ENCODE; ENCBS428ENC
DR   ENCODE; ENCBS433ENC
DR   ENCODE; ENCBS434ENC
DR   ENCODE; ENCBS435ENC
DR   ENCODE; ENCBS436ENC
DR   ENCODE; ENCBS437ENC
DR   ENCODE; ENCBS438ENC
DR   ENCODE; ENCBS439KOM
DR   ENCODE; ENCBS489AAA
DR   ENCODE; ENCBS490AAA
DR   ENCODE; ENCBS491AAA
DR   ENCODE; ENCBS492AAA
DR   ENCODE; ENCBS495AAA
DR   ENCODE; ENCBS500EWH
DR   ENCODE; ENCBS526AQV
DR   ENCODE; ENCBS592MTQ
DR   GDSC; 717431
DR   GEO; GSM231674
DR   GEO; GSM231675
DR   GEO; GSM231676
DR   GEO; GSM231677
DR   GEO; GSM231678
DR   GEO; GSM231679
DR   GEO; GSM231680
DR   GEO; GSM231681
DR   GEO; GSM231682
DR   GEO; GSM231683
DR   GEO; GSM231684
DR   GEO; GSM231685
DR   GEO; GSM231686
DR   GEO; GSM231687
DR   GEO; GSM231688
DR   GEO; GSM231689
DR   GEO; GSM231690
DR   GEO; GSM231691
DR   GEO; GSM231692
DR   GEO; GSM231693
DR   GEO; GSM314027
DR   GEO; GSM333814
DR   GEO; GSM563357
DR   GEO; GSM692864
DR   GEO; GSM803335
DR   GEO; GSM887597
DR   GEO; GSM888680
DR   GEO; GSM923419
DR   GEO; GSM923441
DR   GEO; GSM1003626
DR   GEO; GSM1003627
DR   GEO; GSM1003628
DR   GEO; GSM1003629
DR   GEO; GSM1003630
DR   GEO; GSM1003631
DR   GEO; GSM1003632
DR   GEO; GSM1003633
DR   GEO; GSM1008585
DR   GEO; GSM1010735
DR   GEO; GSM1010738
DR   GEO; GSM1010739
DR   GEO; GSM1010750
DR   GEO; GSM1010751
DR   GEO; GSM1010763
DR   GEO; GSM1010767
DR   GEO; GSM1010773
DR   GEO; GSM1010799
DR   GEO; GSM1010806
DR   GEO; GSM1010816
DR   GEO; GSM1010817
DR   GEO; GSM1010834
DR   GEO; GSM1010835
DR   GEO; GSM1010840
DR   GEO; GSM1010858
DR   GEO; GSM1010880
DR   GEO; GSM1010887
DR   GEO; GSM1010897
DR   GEO; GSM1010900
DR   GEO; GSM1010901
DR   GEO; GSM1622296
DR   GEO; GSM1670454
DR   GEO; GSM2371259
DR   GEO; GSM2394365
DR   GEO; GSM2824362
DR   GEO; GSM2824363
DR   GEO; GSM4104597
DR   GEO; GSM4104598
DR   GEO; GSM4104637
DR   GEO; GSM4104638
DR   IARC_TP53; 23584
DR   ICLC; HTL96019
DR   IZSLER; BS TCL 143
DR   KCB; KCB 200426YJ
DR   KCLB; 30011
DR   LINCS_LDP; LCL-1971
DR   Lonza; 80
DR   PharmacoDB; SKNSH_1409_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_0531
DR   PubChem_Cell_line; CVCL_0531
DR   RCB; RCB0426
DR   TOKU-E; 3149
DR   Ubigene; YC-C027
DR   Wikidata; Q28308636
RX   DOI=10.1007/0-306-46872-7_2;
RX   DOI=10.1007/978-1-4757-1647-4_13;
RX   DOI=10.1016/B978-0-12-333530-2.50006-X;
RX   DOI=10.1159/000407025;
RX   PubMed=29704;
RX   PubMed=62055;
RX   PubMed=833871;
RX   PubMed=922665;
RX   PubMed=1354203;
RX   PubMed=2535691;
RX   PubMed=2846152;
RX   PubMed=2987426;
RX   PubMed=3518877;
RX   PubMed=4748425;
RX   PubMed=6582512;
RX   PubMed=6610792;
RX   PubMed=6888561;
RX   PubMed=6935474;
RX   PubMed=7037175;
RX   PubMed=7838528;
RX   PubMed=8040301;
RX   PubMed=8069455;
RX   PubMed=8490657;
RX   PubMed=8617485;
RX   PubMed=8665486;
RX   PubMed=10074188;
RX   PubMed=10630978;
RX   PubMed=11550280;
RX   PubMed=12702577;
RX   PubMed=15390183;
RX   PubMed=15892104;
RX   PubMed=16822308;
RX   PubMed=18724359;
RX   PubMed=18957096;
RX   PubMed=18923523;
RX   PubMed=18923524;
RX   PubMed=22213050;
RX   PubMed=22460905;
RX   PubMed=23325432;
RX   PubMed=24466371;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25960936;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28350380;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=35839778;
WW   http://genome.ucsc.edu/ENCODE/protocols/cell/human/SK-N-SH_Myers_protocol.pdf
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/s/cell-lines-detail-398.html
WW   https://www.mskcc.org/research-advantage/support/technology/tangible-material/human-neuroblastoma-cell-line-sk-n-sh
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: ENCODE project common cell types; tier 3.
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK1980-529.
CC   Population: Caucasian.
CC   Doubling time: 44 hours (PubMed=4748425).
CC   HLA typing: A*01:01,24:02; B*18:01,49:01; C*07:06,07:06 (PubMed=25960936).
CC   HLA typing: A*01:01,24:02; B*18:01,49:01; C*07:06,07:06 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; 427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Heterozygous (PubMed=18724359; PubMed=18923523; PubMed=28350380; Cosmic-CLP; DepMap).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
CC   Omics: Array-based CGH.
CC   Omics: Chromatin accessibility by ATAC-seq.
CC   Omics: ChIP-seq epigenome analysis.
CC   Omics: CRISPR phenotypic screen.
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=0.37%; Native American=0.07%; East Asian, North=1.63%; East Asian, South=0%; South Asian=0%; European, North=66.77%; European, South=31.16% (PubMed=30894373).
CC   Misspelling: SK-N-CH; Note=Occasionally.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): AddexBio; ATCC; CCRID; Cosmic-CLP; ECACC; Genomics_Center_BCF_Technion; KCLB; PubMed=25877200; RCB
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D10S1248: 14
ST   D12S391: 18,22
ST   D13S317: 11
ST   D16S539: 8,13
ST   D18S51: 13,16
ST   D19S433: 13,14
ST   D1S1656: 12
ST   D21S11: 31,31.2
ST   D22S1045: 16,17
ST   D2S1338: 17,19
ST   D2S441: 11,11.3
ST   D3S1358: 15,16
ST   D5S818: 12
ST   D7S820: 7,10
ST   D8S1179: 15
ST   FGA: 23.2,24
ST   Penta D: 10,12
ST   Penta E: 7,11
ST   TH01: 7,10
ST   TPOX: 8,11
ST   vWA: 14,18
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   4Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 46
//
RX   DOI=10.1007/0-306-46872-7_2;
RA   Thiele C.J.;
RT   "Neuroblastoma.";
RL   (In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York (1999).
//
RX   DOI=10.1007/978-1-4757-1647-4_13;
RA   Biedler J.L.;
RT   "Chromosome abnormalities in human tumor cells in culture.";
RL   (In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975).
//
RX   DOI=10.1016/B978-0-12-333530-2.50006-X;
RA   Israel M.A., Thiele C.J.;
RT   "Tumor cell lines of the peripheral nervous system.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.43-78; Academic Press; New York (1994).
//
RX   DOI=10.1159/000407025;
RA   Helson L., Verma M., Helson C.;
RT   "Vitamin E and human neuroblastoma.";
RL   (In) Modulation and mediation of cancer by vitamins; Meyskens F.L., Prasad K.N. (eds.); pp.258-265; Karger; Basel (1983).
//
RX   PubMed=29704;
RA   Biedler J.L., Roffler-Tarlov S., Schachner M., Freedman L.S.;
RT   "Multiple neurotransmitter synthesis by human neuroblastoma cell lines
RT   and clones.";
RL   Cancer Res. 38:3751-3757(1978).
//
RX   PubMed=62055; DOI=10.1093/jnci/57.3.683;
RA   Biedler J.L., Spengler B.A.;
RT   "A novel chromosome abnormality in human neuroblastoma and
RT   antifolate-resistant Chinese hamster cell lives in culture.";
RL   J. Natl. Cancer Inst. 57:683-695(1976).
//
RX   PubMed=833871; DOI=10.1093/jnci/58.2.209;
RA   Fogh J., Wright W.C., Loveless J.D.;
RT   "Absence of HeLa cell contamination in 169 cell lines derived from
RT   human tumors.";
RL   J. Natl. Cancer Inst. 58:209-214(1977).
//
RX   PubMed=922665; DOI=10.1002/1097-0142(197711)40:5<2256::AID-CNCR2820400536>3.0.CO;2-1;
RA   Brodeur G.M., Sekhon G., Goldstein M.N.;
RT   "Chromosomal aberrations in human neuroblastomas.";
RL   Cancer 40:2256-2263(1977).
//
RX   PubMed=1354203; DOI=10.1002/ijc.2910520116;
RA   Gross N., Favre S., Beck D., Meyer M.;
RT   "Differentiation-related expression of adhesion molecules and
RT   receptors on human neuroblastoma tissues, cell lines and variants.";
RL   Int. J. Cancer 52:85-91(1992).
//
RX   PubMed=2535691;
RA   Ciccarone V., Spengler B.A., Meyers M.B., Biedler J.L., Ross R.A.;
RT   "Phenotypic diversification in human neuroblastoma cells: expression
RT   of distinct neural crest lineages.";
RL   Cancer Res. 49:219-225(1989).
//
RX   PubMed=2846152;
RA   Preis P.N., Saya H., Nadasdi L., Hochhaus G., Levin V., Sadee W.;
RT   "Neuronal cell differentiation of human neuroblastoma cells by
RT   retinoic acid plus herbimycin A.";
RL   Cancer Res. 48:6530-6534(1988).
//
RX   PubMed=2987426; DOI=10.1007/BF00165170;
RA   Helson L., Helson C.;
RT   "Human neuroblastoma cells and 13-cis-retinoic acid.";
RL   J. Neurooncol. 3:39-41(1985).
//
RX   PubMed=3518877; DOI=10.3109/07357908609038260;
RA   Fogh J.;
RT   "Human tumor lines for cancer research.";
RL   Cancer Invest. 4:157-184(1986).
//
RX   PubMed=4748425;
RA   Biedler J.L., Helson L., Spengler B.A.;
RT   "Morphology and growth, tumorigenicity, and cytogenetics of human
RT   neuroblastoma cells in continuous culture.";
RL   Cancer Res. 33:2643-2652(1973).
//
RX   PubMed=6582512; DOI=10.1073/pnas.81.2.568;
RA   Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.;
RT   "Cell surface antigens of human ovarian and endometrial carcinoma
RT   defined by mouse monoclonal antibodies.";
RL   Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984).
//
RX   PubMed=6610792; DOI=10.1093/jnci/73.1.51;
RA   Sugimoto T., Tatsumi E., Kemshead J.T., Helson L., Green A.A.,
RA   Minowada J.;
RT   "Determination of cell surface membrane antigens common to both human
RT   neuroblastoma and leukemia-lymphoma cell lines by a panel of 38
RT   monoclonal antibodies.";
RL   J. Natl. Cancer Inst. 73:51-57(1984).
//
RX   PubMed=6888561; DOI=10.1038/305245a0;
RA   Schwab M., Alitalo K., Klempnauer K.-H., Varmus H.E., Bishop J.M.,
RA   Gilbert F., Brodeur G.M., Goldstein M.N., Trent J.M.;
RT   "Amplified DNA with limited homology to myc cellular oncogene is
RT   shared by human neuroblastoma cell lines and a neuroblastoma tumour.";
RL   Nature 305:245-248(1983).
//
RX   PubMed=6935474; DOI=10.1093/jnci/66.2.239;
RA   Wright W.C., Daniels W.P., Fogh J.;
RT   "Distinction of seventy-one cultured human tumor cell lines by
RT   polymorphic enzyme analysis.";
RL   J. Natl. Cancer Inst. 66:239-247(1981).
//
RX   PubMed=7037175;
RA   Reynolds C.P., Reynolds D.A., Frenkel E.P., Smith R.G.;
RT   "Selective toxicity of 6-hydroxydopamine and ascorbate for human
RT   neuroblastoma in vitro: a model for clearing marrow prior to
RT   autologous transplant.";
RL   Cancer Res. 42:1331-1336(1982).
//
RX   PubMed=7838528;
RA   Cheng N.C., Van Roy N., Chan A., Beitsma M., Westerveld A.,
RA   Speleman F., Versteeg R.;
RT   "Deletion mapping in neuroblastoma cell lines suggests two distinct
RT   tumor suppressor genes in the 1p35-36 region, only one of which is
RT   associated with N-myc amplification.";
RL   Oncogene 10:291-297(1995).
//
RX   PubMed=8040301; DOI=10.1172/JCI117360;
RA   Giovannini M., Biegel J.A., Serra M., Wang J.-Y., Wei Y.-L.H., Nycum L.,
RA   Emanuel B.S., Evans G.A.;
RT   "EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and
RT   primitive neuroectodermal tumors with variant translocations.";
RL   J. Clin. Invest. 94:489-496(1994).
//
RX   PubMed=8069455; DOI=10.1007/BF02631450;
RA   Fukuchi K.-i., Hearn M.G., Deeb S.S., Smith A.C., Ngoc Thao D.,
RA   Miyazaki J.-i., Bothwell M., Martin G.M.;
RT   "Activity assays of nine heterogeneous promoters in neural and other
RT   cultured cells.";
RL   In Vitro Cell. Dev. Biol. Anim. 30:300-305(1994).
//
RX   PubMed=8490657; DOI=10.1038/ng0193-62;
RA   The I., Murthy A.E., Hannigan G.E., Jacoby L.B., Menon A.G.,
RA   Gusella J.F., Bernards A.;
RT   "Neurofibromatosis type 1 gene mutations in neuroblastoma.";
RL   Nat. Genet. 3:62-66(1993).
//
RX   PubMed=8617485; DOI=10.1016/S0046-8177(96)90115-X;
RA   Scotlandi K., Serra M., Manara M.C., Benini S., Sarti M., Maurici D.,
RA   Lollini P.-L., Picci P., Bertoni F., Baldini N.;
RT   "Immunostaining of the p30/32MIC2 antigen and molecular detection of
RT   EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral
RT   neuroectodermal tumor.";
RL   Hum. Pathol. 27:408-416(1996).
//
RX   PubMed=8665486; DOI=10.1016/0304-3835(96)04250-4;
RA   Diccianni M.B., Chau L.S., Batova A., Vu T.Q., Yu A.L.-T.;
RT   "The p16 and p18 tumor suppressor genes in neuroblastoma: implications
RT   for drug resistance.";
RL   Cancer Lett. 104:183-192(1996).
//
RX   PubMed=10074188; DOI=10.1128/JVI.73.4.3338-3350.1999;
RA   Arbour N., Cote G., Lachance C., Tardieu M., Cashman N.R.,
RA   Talbot P.J.;
RT   "Acute and persistent infection of human neural cell lines by human
RT   coronavirus OC43.";
RL   J. Virol. 73:3338-3350(1999).
//
RX   PubMed=10630978; DOI=10.1667/0033-7587(2000)153[0062:FORIMI]2.0.CO;2;
RA   Akudugu J.M., Slabbert J.P., Serafin A., Bohm L.;
RT   "Frequency of radiation-induced micronuclei in neuronal cells does not
RT   correlate with clonogenic survival.";
RL   Radiat. Res. 153:62-67(2000).
//
RX   PubMed=11550280; DOI=10.1002/gcc.1174;
RA   Van Roy N., Van Limbergen H., Vandesompele J., Van Gele M., Poppe B.,
RA   Salwen H.R., Laureys G., Manoel N., De Paepe A., Speleman F.;
RT   "Combined M-FISH and CGH analysis allows comprehensive description of
RT   genetic alterations in neuroblastoma cell lines.";
RL   Genes Chromosomes Cancer 32:126-135(2001).
//
RX   PubMed=12702577;
RA   Saito-Ohara F., Imoto I., Inoue J., Hosoi H., Nakagawara A.,
RA   Sugimoto T., Inazawa J.;
RT   "PPM1D is a potential target for 17q gain in neuroblastoma.";
RL   Cancer Res. 63:1876-1883(2003).
//
RX   PubMed=15390183; DOI=10.1002/gcc.20096;
RA   Gebauer S., Yu A.L.-T., Omura-Minamisawa M., Batova A., Diccianni M.B.;
RT   "Expression profiles and clinical relationships of ID2, CDKN1B, and
RT   CDKN2A in primary neuroblastoma.";
RL   Genes Chromosomes Cancer 41:297-308(2004).
//
RX   PubMed=15892104; DOI=10.1002/gcc.20198;
RA   Mosse Y.P., Greshock J., Margolin A.A., Naylor T., Cole K., Khazi D.,
RA   Hii G., Winter C., Shahzad S., Asziz M.U., Biegel J.A., Weber B.L.,
RA   Maris J.M.;
RT   "High-resolution detection and mapping of genomic DNA alterations in
RT   neuroblastoma.";
RL   Genes Chromosomes Cancer 43:390-403(2005).
//
RX   PubMed=16822308; DOI=10.1186/1471-2407-6-177;
RA   Dam V., Morgan B.T., Mazanek P., Hogarty M.D.;
RT   "Mutations in PIK3CA are infrequent in neuroblastoma.";
RL   BMC Cancer 6:177.1-177.10(2006).
//
RX   PubMed=18724359; DOI=10.1038/nature07261;
RA   Mosse Y.P., Laudenslager M., Longo L., Cole K.A., Wood A.,
RA   Attiyeh E.F., Laquaglia M.J., Sennett R., Lynch J.E., Perri P.,
RA   Laureys G., Speleman F., Kim C., Hou C.-P., Hakonarson H., Torkamani A.,
RA   Schork N.J., Brodeur G.M., Tonini G.P., Rappaport E., Devoto M.,
RA   Maris J.M.;
RT   "Identification of ALK as a major familial neuroblastoma
RT   predisposition gene.";
RL   Nature 455:930-935(2008).
//
RX   PubMed=18957096; DOI=10.1186/1756-0500-1-95;
RA   Nishida Y., Adati N., Ozawa R., Maeda A., Sakaki Y., Takeda T.;
RT   "Identification and classification of genes regulated by
RT   phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways
RT   during neuronal differentiation in two subtypes of the human
RT   neuroblastoma cell line SH-SY5Y.";
RL   BMC Res. Notes 1:95.1-95.11(2008).
//
RX   PubMed=18923523; DOI=10.1038/nature07398;
RA   Janoueix-Lerosey I., Lequin D., Brugieres L., Ribeiro A.,
RA   de Pontual L., Combaret V., Raynal V., Puisieux A., Schleiermacher G.,
RA   Pierron G., Valteau-Couanet D., Frebourg T., Michon J., Lyonnet S.,
RA   Amiel J., Delattre O.;
RT   "Somatic and germline activating mutations of the ALK kinase receptor
RT   in neuroblastoma.";
RL   Nature 455:967-970(2008).
//
RX   PubMed=18923524; DOI=10.1038/nature07399;
RA   Chen Y.-Y., Takita J., Choi Y.L., Kato M., Ohira M., Sanada M.,
RA   Wang L.-L., Soda M., Kikuchi A., Igarashi T., Nakagawara A.,
RA   Hayashi Y., Mano H., Ogawa S.;
RT   "Oncogenic mutations of ALK kinase in neuroblastoma.";
RL   Nature 455:971-974(2008).
//
RX   PubMed=22213050; DOI=10.1002/ijc.27415;
RA   Gawecka J.E., Geerts D., Koster J., Caliva M.J., Sulzmaier F.J.,
RA   Opoku-Ansah J., Wada R.K., Bachmann A.S., Ramos J.W.;
RT   "PEA15 impairs cell migration and correlates with clinical features
RT   predicting good prognosis in neuroblastoma.";
RL   Int. J. Cancer 131:1556-1568(2012).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
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