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Cellosaurus SqCC/Y1 (CVCL_0551)

Cell line name SqCC/Y1
Synonyms SqCC-Y1; SQCCY1
Accession CVCL_0551
Resource Identification Initiative To cite this cell line use: SqCC/Y1 (RRID:CVCL_0551)
Comments Part of: MD Anderson Cell Lines Project.
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by RNAseq.
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=21868764

Markers:
AmelogeninX
CSF1PO9,11
D5S81812,13
D7S8208,11
D13S31711
D16S53911,13
TH017,9.3
TPOX8
vWA15,16

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=3858572; DOI=10.1093/jnci/74.5.1015
Reiss M., Pitman S.W., Sartorelli A.C.
Modulation of the terminal differentiation of human squamous carcinoma cells in vitro by all-trans-retinoic acid.
J. Natl. Cancer Inst. 74:1015-1023(1985)

PubMed=11377230; DOI=10.1016/S1368-8375(00)00089-0
Hansson A., Bloor B.K., Haig Y., Morgan P.R., Ekstrand J., Grafstrom R.C.
Expression of keratins in normal, immortalized and malignant oral epithelia in organotypic culture.
Oral Oncol. 37:419-430(2001)

PubMed=18186669; DOI=10.1177/026119290703500603
Ceder R., Merne M., Staab C.A., Nilsson J.A., Hoog J.-O., Dressler D., Engelhart K., Grafstrom R.C.
The application of normal, SV40 T-antigen-immortalised and tumour-derived oral keratinocytes, under serum-free conditions, to the study of the probability of cancer progression as a result of environmental exposure to chemicals.
Altern. Lab. Anim. 35:621-639(2007)

CLPUB00346
Ceder R.
Cancer biomarker discovery by in vitro systems biology.
Thesis PhD (2011), Karolinska Institutet, Sweden

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=26754630; DOI=10.1186/s13046-016-0284-4
Hyakusoku H., Sano D., Takahashi H., Hatano T., Isono Y., Shimada S., Ito Y., Myers J.N., Oridate N.
JunB promotes cell invasion, migration and distant metastasis of head and neck squamous cell carcinoma.
J. Exp. Clin. Cancer Res. 35:6.1-6.12(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29156801; DOI=10.18632/oncotarget.21174
Kalu N.N., Mazumdar T., Peng S.-H., Shen L., Sambandam V., Rao X.-Y., Xi Y.-X., Li L.-R., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-2980 - Discontinued
Cell line databases/resources MCCL; MCC:0000452
Encyclopedic resources Wikidata; Q54955611
Gene expression databases GEO; GSM190621
GEO; GSM190622
GEO; GSM966940
GEO; GSM966941
GEO; GSM966946
Polymorphism and mutation databases Cosmic; 948040
Cosmic; 2131856
Cosmic; 2513918
Cosmic; 2602602
Cosmic; 2646651
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number14