Cellosaurus TF-1 (CVCL_0559)

Cell line name TF-1
Synonyms TF1
Accession CVCL_0559
Resource Identification Initiative To cite this cell line use: TF-1 (RRID:CVCL_0559)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Characteristics: Proliferatively responsive to many growth factors.
Characteristics: IL3 or CSF2 dependent.
Doubling time: ~70 hours (DSMZ).
Sequence variation: Homozygous for JAK2 p.Val617Phe (PubMed=16408098).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Bone marrow.
Disease Erythroleukemia (NCIt: C7152)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_KS74 (CellSensor irf1-bla TF1); CVCL_8059 (D2 [Human erythroleukemia]); CVCL_8060 (D8); CVCL_J294 (TF-1 BCR/ABL); CVCL_3607 (TF-1.CN5a.1); CVCL_3608 (TF-1a)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; CLS; DSMZ; ECACC; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO13,14 (ATCC; PubMed=25877200)
13 (CLS; DSMZ; ECACC)
D13S3178,9
D16S5399,12
D18S5113
D21S1130
D3S135815
D5S81813
D7S82012
D8S117911,15
FGA18,19
Penta D10,13
Penta E5,17
TH017,9
TPOX8
vWA15,17
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=TF-1
Publications

PubMed=2656885; DOI=10.1002/stem.5530070202
Ihle J.N., Askew D.
Origins and properties of hematopoietic growth factor-dependent cell lines.
Int. J. Cell Cloning 7:68-91(1989)

PubMed=2663885; DOI=10.1002/jcp.1041400219
Kitamura T., Tange T., Terasawa T., Chiba S., Kuwaki T., Miyagawa K., Piao Y.-F., Miyazono K., Urabe A., Takaku F.
Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin.
J. Cell. Physiol. 140:323-334(1989)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

PubMed=11414198; DOI=10.1007/s004320000207
Lahm H., Andre S., Hoeflich A., Fischer J.R., Sordat B., Kaltner H., Wolf E., Gabius H.J.
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.
J. Cancer Res. Clin. Oncol. 127:375-386(2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23955599; DOI=10.1038/ng.2731
Kon A., Shih L.-Y., Minamino M., Sanada M., Shiraishi Y., Nagata Y., Yoshida K., Okuno Y., Bando M., Nakato R., Ishikawa S., Sato-Otsubo A., Nagae G., Nishimoto A., Haferlach C., Nowak D., Sato Y., Alpermann T., Nagasaki M., Shimamura T., Tanaka H., Chiba K., Yamamoto R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Nakamaki T., Ishiyama K., Nolte F., Hofmann W.K., Miyawaki S., Chiba S., Mori H., Nakauchi H., Koeffler H.P., Aburatani H., Haferlach T., Shirahige K., Miyano S., Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

Cross-references
Cell line collections ATCC; CRL-2003
BCRC; 60323
BCRJ; 0233 - Discontinued
CLS; 300434/p538_TF-1
DSMZ; ACC-334
ECACC; 93022307
ICLC; HTL05001
NCBI_Iran; C602
Cell line databases/resources CLDB; cl4503
CLDB; cl7163
CCLE; TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
CCRID; 3111C0001CCC000118
CCRID; 3131C0001000700139
GDSC; 1331044
LINCS_LDP; LCL-1077
Ontologies BTO; BTO:0004760
CLO; CLO_0009325
CLO; CLO_0009326
MCCL; MCC:0000460
Biological sample resources BioSample; SAMN03470850
Chemistry resources ChEMBL-Cells; CHEMBL3307972
ChEMBL-Targets; CHEMBL612552
Gene expression databases GEO; GSM887704
GEO; GSM888797
GEO; GSM1374961
Polymorphism and mutation databases Cosmic; 787479
Cosmic; 919129
Cosmic; 924041
Cosmic; 975302
Cosmic; 1012123
Cosmic; 1127259
Cosmic; 1281355
Cosmic; 2089658
Cosmic; 2306240